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Adejumo OA, Daniel OJ, Otesanya AF, et al. FACTORS ASSOCIATED WITH TB/HIV CO-INFECTION AMONG DRUG SENSITIVE TUBERCULOSIS PATIENTS MANAGED IN A SECONDARY HEALTH FACILITY IN LAGOS, NIGERIA. Afr J Infect Dis. 2017;11(2):75-82doi: 10.21010/ajid.v11i2.10.
Adejumo, O. A., Daniel, O. J., Otesanya, A. F., Adegbola, A. A., Femi-Adebayo, T., Bowale, A., Adesola, S., Kuku, O. O., Otemuyiwa, K. O., Oladega, S. N., Johnson, E. O., Falana, A. A., Dawodu, O., Owuna, H., Osoba, G., & Dacosta, A. (2017). FACTORS ASSOCIATED WITH TB/HIV CO-INFECTION AMONG DRUG SENSITIVE TUBERCULOSIS PATIENTS MANAGED IN A SECONDARY HEALTH FACILITY IN LAGOS, NIGERIA. African journal of infectious diseases, 11(2), 75-82. https://doi.org/10.21010/ajid.v11i2.10
Adejumo, Olusola A, et al. "FACTORS ASSOCIATED WITH TB/HIV CO-INFECTION AMONG DRUG SENSITIVE TUBERCULOSIS PATIENTS MANAGED IN A SECONDARY HEALTH FACILITY IN LAGOS, NIGERIA." African journal of infectious diseases vol. 11,2 (2017): 75-82. doi: https://doi.org/10.21010/ajid.v11i2.10
Adejumo OA, Daniel OJ, Otesanya AF, Adegbola AA, Femi-Adebayo T, Bowale A, Adesola S, Kuku OO, Otemuyiwa KO, Oladega SN, Johnson EO, Falana AA, Dawodu O, Owuna H, Osoba G, Dacosta A. FACTORS ASSOCIATED WITH TB/HIV CO-INFECTION AMONG DRUG SENSITIVE TUBERCULOSIS PATIENTS MANAGED IN A SECONDARY HEALTH FACILITY IN LAGOS, NIGERIA. Afr J Infect Dis. 2017 Jun 08;11(2):75-82. doi: 10.21010/ajid.v11i2.10. eCollection 2017. PMID: 28670643; PMCID: PMC5476816.
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Afr J Infect Dis. 2017 Jun 08;11(2):75-82. doi: 10.21010/ajid.v11i2.10. eCollection 2017.

FACTORS ASSOCIATED WITH TB/HIV CO-INFECTION AMONG DRUG SENSITIVE TUBERCULOSIS PATIENTS MANAGED IN A SECONDARY HEALTH FACILITY IN LAGOS, NIGERIA.

African journal of infectious diseases

Olusola A Adejumo, Olusoji J Daniel, Andrew F Otesanya, Adebukola A Adegbola, Temitope Femi-Adebayo, Abimbola Bowale, Sunday Adesola, Olugbenga O Kuku, Kehinde O Otemuyiwa, Shafaatu N Oladega, Eze O Johnson, Ayodeji A Falana, Olusola Dawodu, Henry Owuna, Ganiyat Osoba, Adetokunbo Dacosta

Affiliations

  1. Department of Community Health and Primary Health Care, Lagos State University Teaching Hospital, Ikeja Lagos, Nigeria.
  2. Department of Community Medicine and Primary Care, Olabisi Onabanjo University Teaching Hospital Sagamu Ogun State.
  3. Medical Services Department, Central Bank of Nigeria, Lagos.
  4. KNCV TB Foundation Nigeria/Challenge TB project, Abuja, Nigeria.
  5. Mainland Hospital, Yaba, Lagos, Nigeria.

PMID: 28670643 PMCID: PMC5476816 DOI: 10.21010/ajid.v11i2.10

Abstract

BACKGROUND: This study assessed factors associated with TB/HIV co-infection among TB patients managed in a secondary health facility in Lagos Nigeria.

MATERIALS AND METHODS: A retrospective review of treatment cards of patients seen at a secondary referral hospital between January 1 2014 and December 31 2014 was conducted. Treatment outcomes and factors associated with TB/HIV co-infection were assessed.

RESULTS: Of the 334 records of patients reviewed, the proportion of patients with TB/HIV co-infection was 21.6%. The odds of having TB/HIV co-infection was 2.7 times higher among patients above 40 years than patients less than 25 years (AOR 2.7 95% CI 1.1 - 6.5, p =0.030). In addition, the odds of having TB/HIV co-infection was 3.3 higher among extra-pulmonary TB cases (AOR 3.3; 95% CI 1.2 - 9.5; p = 0.026) and 2.1 times higher among retreated patients (AOR 2.1; 95% CI 1.1 - 3.9; p = 0.017) than pulmonary TB and new patients respectively. The chance of having TB/HIV co-infection was 2.7-fold more in patients with poor treatment outcomes than patients with treatment success (AOR 2.7; 95%CI 1.3 - 5.4; p =0.006).

CONCLUSION: TB/HIV co-infection rate was high in the study area. There is need to put measures in place to improve treatment outcomes of TB/HIV co-infected patients.

Keywords: HIV; Nigeria; TB; co-infection

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