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Butorina AV, Pavlova AA, Nikolaeva AY, et al. Simultaneous Processing of Noun Cue and to-be-Produced Verb in Verb Generation Task: Electromagnetic Evidence. Front Hum Neurosci. 2017;11:279doi: 10.3389/fnhum.2017.00279.
Butorina, A. V., Pavlova, A. A., Nikolaeva, A. Y., Prokofyev, A. O., Bondarev, D. P., & Stroganova, T. A. (2017). Simultaneous Processing of Noun Cue and to-be-Produced Verb in Verb Generation Task: Electromagnetic Evidence. Frontiers in human neuroscience, 11279. https://doi.org/10.3389/fnhum.2017.00279
Butorina, Anna V, et al. "Simultaneous Processing of Noun Cue and to-be-Produced Verb in Verb Generation Task: Electromagnetic Evidence." Frontiers in human neuroscience vol. 11 (2017): 279. doi: https://doi.org/10.3389/fnhum.2017.00279
Butorina AV, Pavlova AA, Nikolaeva AY, Prokofyev AO, Bondarev DP, Stroganova TA. Simultaneous Processing of Noun Cue and to-be-Produced Verb in Verb Generation Task: Electromagnetic Evidence. Front Hum Neurosci. 2017 May 30;11:279. doi: 10.3389/fnhum.2017.00279. eCollection 2017. PMID: 28611613; PMCID: PMC5447679.
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Front Hum Neurosci. 2017 May 30;11:279. doi: 10.3389/fnhum.2017.00279. eCollection 2017.

Simultaneous Processing of Noun Cue and to-be-Produced Verb in Verb Generation Task: Electromagnetic Evidence.

Frontiers in human neuroscience

Anna V Butorina, Anna A Pavlova, Anastasia Y Nikolaeva, Andrey O Prokofyev, Denis P Bondarev, Tatiana A Stroganova

Affiliations

  1. MEG Center, Moscow State University of Psychology and EducationMoscow, Russia.
  2. National Research Center "Kurchatov Institute"Moscow, Russia.

PMID: 28611613 PMCID: PMC5447679 DOI: 10.3389/fnhum.2017.00279

Abstract

A long-standing but implicit assumption is that words strongly associated with a presented cue are automatically activated in the memory through rapid spread of activation within brain semantic networks. The current study was aimed to provide direct evidence of such rapid access to words' semantic representations and to investigate its neural sources using magnetoencephalography (MEG) and distributed source localization technique. Thirty-three neurotypical subjects underwent the MEG recording during verb generation task, which was to produce verbs related to the presented noun cues. Brain responses evoked by the noun cues were examined while manipulating the strength of association between the noun and the potential verb responses. The strong vs. weak noun-verb association led to a greater noun-related neural response at 250-400 ms after cue onset, and faster verb production. The cortical sources of the differential response were localized in left temporal pole, previously implicated in semantic access, and left ventrolateral prefrontal cortex (VLPFC), thought to subserve controlled semantic retrieval. The strength of the left VLPFC's response to the nouns with strong verb associates was positively correlated to the speed of verbs production. Our findings empirically validate the theoretical expectation that in case of a strongly connected noun-verb pair, successful access to target verb representation may occur already at the stage of lexico-semantic analysis of the presented noun. Moreover, the MEG results suggest that contrary to the previous conclusion derived from fMRI studies left VLPFC supports selection of the target verb representations, even if they were retrieved from semantic memory rapidly and effortlessly. The discordance between MEG and fMRI findings in verb generation task may stem from different modes of neural activation captured by phase-locked activity in MEG and slow changes of blood-oxygen-level-dependent (BOLD) signal in fMRI.

Keywords: association; lexical–semantic processing; magnetoencephalography (MEG); semantic retrieval; verb generation; word production

References

  1. Brain. 2010 Jan;133(Pt 1):46-59 - PubMed
  2. Proc Biol Sci. 2001 Nov 7;268(1482):2261-5 - PubMed
  3. J Cogn Neurosci. 2008 Sep;20(9):1727-36 - PubMed
  4. J Neurosci. 1995 Feb;15(2):1080-9 - PubMed
  5. Neuron. 2000 Apr;26(1):55-67 - PubMed
  6. Philos Trans R Soc Lond B Biol Sci. 2013 Dec 09;369(1634):20120392 - PubMed
  7. Lang Linguist Compass. 2009 Jan 1;3(1):128-156 - PubMed
  8. J Neurosci. 2013 Oct 23;33(43):17174-81 - PubMed
  9. Neuropsychologia. 2009 Jan;47(1):1-16 - PubMed
  10. Nature. 1994 Nov 17;372(6503):260-3 - PubMed
  11. Neuropsychologia. 2007 Oct 1;45(13):2883-901 - PubMed
  12. Phys Med Biol. 1999 Feb;44(2):423-40 - PubMed
  13. J Neurosci. 2009 Nov 4;29(44):13962-70 - PubMed
  14. J Cogn Neurosci. 2004 Sep;16(7):1250-61 - PubMed
  15. Nat Rev Neurosci. 2008 Dec;9(12 ):920-33 - PubMed
  16. Neuroimage. 2009 Feb 1;44(3):1093-102 - PubMed
  17. Annu Rev Neurosci. 1995;18:193-222 - PubMed
  18. Trends Cogn Sci. 2011 Jun;15(6):254-62 - PubMed
  19. Neuron. 2001 Aug 2;31(2):329-38 - PubMed
  20. J Speech Lang Hear Res. 2008 Oct;51(5):1183-202 - PubMed
  21. Neuroimage. 2002 Nov;17(3):1101-16 - PubMed
  22. Psychol Rev. 2004 Jan;111(1):205-35 - PubMed
  23. Nat Rev Neurosci. 2007 Dec;8(12):976-87 - PubMed
  24. Brain. 1999 Nov;122 ( Pt 11):2119-32 - PubMed
  25. Brain Res Cogn Brain Res. 2004 Mar;19(1):59-73 - PubMed
  26. Psychon Bull Rev. 2006 Jun;13(3):396-401 - PubMed
  27. Comput Intell Neurosci. 2011;2011:879716 - PubMed
  28. Trends Cogn Sci. 2000 Dec 1;4(12):463-470 - PubMed
  29. Cereb Cortex. 2011 May;21(5):1066-75 - PubMed
  30. J Cogn Neurosci. 2006 Oct;18(10):1631-43 - PubMed
  31. Cogn Affect Behav Neurosci. 2004 Mar;4(1):43-57 - PubMed
  32. Trends Cogn Sci. 2005 Sep;9(9):416-23 - PubMed
  33. Cogn Sci. 2005 Jan 2;29(1):41-78 - PubMed
  34. Clin Neurophysiol. 2007 Feb;118(2):237-54 - PubMed
  35. Electroencephalogr Clin Neurophysiol. 1993 May-Jun;88(3):210-9 - PubMed
  36. Med Biol Eng Comput. 1994 Jan;32(1):35-42 - PubMed
  37. Neuroimage. 2012 Feb 1;59(3):2600-6 - PubMed
  38. Annu Rev Psychol. 2011;62:621-47 - PubMed
  39. Trends Cogn Sci. 2014 Feb;18(2):90-8 - PubMed
  40. Cereb Cortex. 2004 Aug;14(8):881-91 - PubMed
  41. Neuroimage. 2008 Feb 1;39(3):1104-20 - PubMed
  42. J Cogn Neurosci. 2015 Jul;27(7):1388-96 - PubMed
  43. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2717-22 - PubMed
  44. Cereb Cortex. 2009 Sep;19(9):2156-65 - PubMed
  45. Brain Lang. 1988 Sep;35(1):66-85 - PubMed
  46. Behav Cogn Neurosci Rev. 2002 Sep;1(3):206-18 - PubMed
  47. Brain. 2002 May;125(Pt 5):1125-36 - PubMed
  48. J Cogn Neurosci. 2000 Mar;12(2):298-309 - PubMed
  49. Cereb Cortex. 2009 Dec;19(12):2767-96 - PubMed
  50. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14792-7 - PubMed
  51. Front Psychol. 2011 Oct 12;2:255 - PubMed
  52. Neuroimage. 2012 Aug 15;62(2):1121-30 - PubMed
  53. Nature. 2009 Jan 22;457(7228):475-9 - PubMed
  54. Annu Rev Neurosci. 2014;37:347-62 - PubMed
  55. Brain Lang. 2001 Mar;76(3):340-50 - PubMed
  56. Psychon Bull Rev. 2008 Dec;15(6):1083-8 - PubMed
  57. Nature. 2001 Jul 12;412(6843):150-7 - PubMed
  58. Brain Lang. 2009 Aug;110(2):81-94 - PubMed
  59. Clin Neurophysiol. 2004 May;115(5):1090-103 - PubMed
  60. J Cogn Neurosci. 2010 Jun;22(6):1140-57 - PubMed
  61. Neuroreport. 2002 Mar 4;13(3):321-5 - PubMed
  62. Behav Brain Funct. 2005 Aug 09;1:13 - PubMed
  63. Neuroimage. 2004 Dec;23(4):1382-90 - PubMed
  64. J Cogn Neurosci. 2011 Nov;23(11):3470-82 - PubMed
  65. Behav Res Methods Instrum Comput. 2004 Aug;36(3):402-7 - PubMed

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