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Ueno M, Matsumoto S, Matsumoto A, et al. Effect of amifostine, a radiation-protecting drug, on oxygen concentration in tissue measured by EPR oximetry and imaging. J Clin Biochem Nutr. 2017;60(3):151-155doi: 10.3164/jcbn.15-130.
Ueno, M., Matsumoto, S., Matsumoto, A., Manda, S., Nakanishi, I., Matsumoto, K. I., Mitchell, J. B., Krishna, M. C., & Anzai, K. (2017). Effect of amifostine, a radiation-protecting drug, on oxygen concentration in tissue measured by EPR oximetry and imaging. Journal of clinical biochemistry and nutrition, 60(3), 151-155. https://doi.org/10.3164/jcbn.15-130
Ueno, Megumi, et al. "Effect of amifostine, a radiation-protecting drug, on oxygen concentration in tissue measured by EPR oximetry and imaging." Journal of clinical biochemistry and nutrition vol. 60,3 (2017): 151-155. doi: https://doi.org/10.3164/jcbn.15-130
Ueno M, Matsumoto S, Matsumoto A, Manda S, Nakanishi I, Matsumoto KI, Mitchell JB, Krishna MC, Anzai K. Effect of amifostine, a radiation-protecting drug, on oxygen concentration in tissue measured by EPR oximetry and imaging. J Clin Biochem Nutr. 2017 May;60(3):151-155. doi: 10.3164/jcbn.15-130. Epub 2017 Mar 25. PMID: 28584395; PMCID: PMC5453015.
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J Clin Biochem Nutr. 2017 May;60(3):151-155. doi: 10.3164/jcbn.15-130. Epub 2017 Mar 25.

Effect of amifostine, a radiation-protecting drug, on oxygen concentration in tissue measured by EPR oximetry and imaging.

Journal of clinical biochemistry and nutrition

Megumi Ueno, Shingo Matsumoto, Atsuko Matsumoto, Sushma Manda, Ikuo Nakanishi, Ken-Ichiro Matsumoto, James B Mitchell, Murali C Krishna, Kazunori Anzai

Affiliations

  1. Radio-Redox-Response Research Team, Advanced Particle Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba-shi, Chiba 263-8555, Japan.
  2. Radiation Biology Branch, Center for Cancer Research, National Cancer Institute, Building 10, NIH, Bethesda, MD 20892-1002, USA.
  3. Nihon Pharmaceutical University, 10281 Komuro, Ina-machi, Kitaadachi-gun, Saitama 362-0806, Japan.

PMID: 28584395 PMCID: PMC5453015 DOI: 10.3164/jcbn.15-130

Abstract

Effect of amifostine, a radiation-protecting drug, on muscle tissue partial pressure of oxygen was investigated by electron paramagnetic resonance spectroscopy and imaging. When amifostine was administered intraperitoneally or intravenously to mice, the linewidth of the electron paramagnetic resonance spectra of the lithium octa-

Keywords: EPR imaging; EPR oximetry; amifostine; hypoxia; radioprotector

Conflict of interest statement

No potential conflicts of interest were disclosed.

References

  1. Int J Radiat Oncol Biol Phys. 2001 Jun 1;50(2):473-8 - PubMed
  2. Magn Reson Med Sci. 2007;6(2):83-9 - PubMed
  3. Lymphology. 2010 Jun;43(2):48-58 - PubMed
  4. Eur J Cancer Care (Engl). 2009 Mar;18(2):116-23 - PubMed
  5. Radiat Res. 1989 Jun;118(3):581-6 - PubMed
  6. Radiat Res. 1974 Aug;59(2):475-83 - PubMed
  7. Biochem Soc Trans. 2003 Dec;31(Pt 6):1337-9 - PubMed
  8. Antioxid Redox Signal. 2004 Jun;6(3):597-603 - PubMed
  9. J Physiol. 1954 Nov 29;126(2):15-6P - PubMed
  10. Oncol Rep. 1999 Nov-Dec;6(6):1357-62 - PubMed
  11. J Radiat Res. 2000 Jun;41(2):103-11 - PubMed
  12. Arch Biochem Biophys. 1991 Aug 15;289(1):62-70 - PubMed
  13. Free Radic Biol Med. 2003 Nov 1;35(9):1138-48 - PubMed
  14. Radiother Oncol. 2006 Jun;79(3):352 - PubMed
  15. Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):796-800 - PubMed
  16. Magn Reson Med. 2005 Dec;54(6):1530-5 - PubMed
  17. J Clin Pharmacol. 1996 Apr;36(4):365-73 - PubMed
  18. Int J Radiat Oncol Biol Phys. 1986 Feb;12(2):211-9 - PubMed
  19. Drug Metabol Drug Interact. 2000;16(4):237-79 - PubMed
  20. Cancer Res. 1980 May;40(5):1519-24 - PubMed
  21. Oncologist. 2010;15(4):360-71 - PubMed
  22. Radiother Oncol. 2007 Jan;82(1):110-1; author reply 111 - PubMed
  23. Eur J Cancer. 1996;32A Suppl 4:S26-30 - PubMed
  24. Br J Cancer. 1999 May;80(5-6):629-38 - PubMed
  25. Oncologist. 2007 Jun;12(6):738-47 - PubMed
  26. Magn Reson Med. 2004 Oct;52(4):885-92 - PubMed
  27. Science. 1949 Aug 26;110(2852):213-4 - PubMed
  28. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2216-21 - PubMed
  29. Biochim Biophys Acta. 2003 Mar 20;1637(2):151-5 - PubMed
  30. Mutat Res. 2000 Jun 22;468(1):27-33 - PubMed
  31. Magn Reson Med. 2006 May;55(5):1157-63 - PubMed
  32. Radiat Res. 1987 Mar;109(3):469-78 - PubMed
  33. Anticancer Drugs. 2002 Mar;13(3):327-30 - PubMed
  34. Radiat Res. 1983 May;94(2):239-51 - PubMed
  35. Adv Exp Med Biol. 2014;812:73-9 - PubMed

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