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Case Rep Pathol. 2017;2017:7031414. doi: 10.1155/2017/7031414. Epub 2017 May 11.

Hybrid Desmoplastic/Follicular Ameloblastoma of the Mandible: A Case Report and Review of the Literature.

Case reports in pathology

Masayasu Iwase, Airi Fukuoka, Yoko Tanaka, Naoyuki Saida, Eriko Onaka, Sanae Bando, Gen Kondo

Affiliations

  1. Department of Dentistry and Oral Surgery, Hakujikai Memorial General Hospital, Tokyo, Japan.
  2. Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, Kanagawa, Japan.
  3. Department of Dentistry and Oral Surgery, Jinkokai Hospital, Kanagawa, Japan.

PMID: 28584671 PMCID: PMC5443997 DOI: 10.1155/2017/7031414

Abstract

Desmoplastic ameloblastoma (DA) is one of the 6 histopathological subtypes of ameloblastoma. Hybrid lesions in which histopathologically conventional ameloblastoma coexists with areas of DA are rare. A 40-year-old male was referred to our hospital complaining of a swelling in the right premolar region of the mandible. A panoramic radiograph showed an area of radiolucency with a well-defined corticated border, whereas computed tomography revealed a unilocular radiolucent lesion and buccal expansion together with cortical perforation. The lesion was treated via enucleation and curettage of the marginal bone and fenestration. A histopathological examination showed a hybrid ameloblastoma with a pronounced desmoplastic pattern and follicular changes. The patient's postoperative course has been favorable up to now, and no marked changes have been observed. We presented a case of hybrid ameloblastoma and reviewed the 36 reported cases of hybrid ameloblastoma that have been reported in the English literature.

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