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Ishiya K, Ueda S. MitoSuite: a graphical tool for human mitochondrial genome profiling in massive parallel sequencing. PeerJ. 2017;5:e3406doi: 10.7717/peerj.3406.
Ishiya, K., & Ueda, S. (2017). MitoSuite: a graphical tool for human mitochondrial genome profiling in massive parallel sequencing. PeerJ, 5e3406. https://doi.org/10.7717/peerj.3406
Ishiya, Koji, and Ueda, Shintaroh. "MitoSuite: a graphical tool for human mitochondrial genome profiling in massive parallel sequencing." PeerJ vol. 5 (2017): e3406. doi: https://doi.org/10.7717/peerj.3406
Ishiya K, Ueda S. MitoSuite: a graphical tool for human mitochondrial genome profiling in massive parallel sequencing. PeerJ. 2017 May 30;5:e3406. doi: 10.7717/peerj.3406. eCollection 2017. PMID: 28584729; PMCID: PMC5452969.
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PeerJ. 2017 May 30;5:e3406. doi: 10.7717/peerj.3406. eCollection 2017.

MitoSuite: a graphical tool for human mitochondrial genome profiling in massive parallel sequencing.

PeerJ

Koji Ishiya, Shintaroh Ueda

Affiliations

  1. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.

PMID: 28584729 PMCID: PMC5452969 DOI: 10.7717/peerj.3406

Abstract

Recent rapid advances in high-throughput, next-generation sequencing (NGS) technologies have promoted mitochondrial genome studies in the fields of human evolution, medical genetics, and forensic casework. However, scientists unfamiliar with computer programming often find it difficult to handle the massive volumes of data that are generated by NGS. To address this limitation, we developed MitoSuite, a user-friendly graphical tool for analysis of data from high-throughput sequencing of the human mitochondrial genome. MitoSuite generates a visual report on NGS data with simple mouse operations. Moreover, it analyzes high-coverage sequencing data but runs on a stand-alone computer, without the need for file upload. Therefore, MitoSuite offers outstanding usability for handling massive NGS data, and is ideal for evolutionary, clinical, and forensic studies on the human mitochondrial genome variations. It is freely available for download from the website https://mitosuite.com.

Keywords: Graphical tool; Massively parallel sequencing; MitoSuite; Mitochondrial genome; Next-generation sequencing

Conflict of interest statement

The authors declare there are no competing interests.

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