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Uddin LQ, Nomi JS, Hébert-Seropian B, et al. Structure and Function of the Human Insula. J Clin Neurophysiol. 2017;34(4):300-306doi: 10.1097/WNP.0000000000000377.
Uddin, L. Q., Nomi, J. S., Hébert-Seropian, B., Ghaziri, J., & Boucher, O. (2017). Structure and Function of the Human Insula. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 34(4), 300-306. https://doi.org/10.1097/WNP.0000000000000377
Uddin, Lucina Q, et al. "Structure and Function of the Human Insula." Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society vol. 34,4 (2017): 300-306. doi: https://doi.org/10.1097/WNP.0000000000000377
Uddin LQ, Nomi JS, Hébert-Seropian B, Ghaziri J, Boucher O. Structure and Function of the Human Insula. J Clin Neurophysiol. 2017 Jul;34(4):300-306. doi: 10.1097/WNP.0000000000000377. PMID: 28644199; PMCID: PMC6032992.
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J Clin Neurophysiol. 2017 Jul;34(4):300-306. doi: 10.1097/WNP.0000000000000377.

Structure and Function of the Human Insula.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society

Lucina Q Uddin, Jason S Nomi, Benjamin Hébert-Seropian, Jimmy Ghaziri, Olivier Boucher

Affiliations

  1. *Department of Psychology, University of Miami, Coral Gables, Florida, U.S.A.; †Neuroscience Program, Miller School of Medicine, University of Miami, Miami, Florida, U.S.A.; ‡Department of Psychology, Université de Montréal, Montréal, QC, Canada; §Department of Psychology, Université du Québec à Montréal, Montréal, QC, Canada; and ?Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.

PMID: 28644199 PMCID: PMC6032992 DOI: 10.1097/WNP.0000000000000377

Abstract

The insular cortex, or "Island of Reil," is hidden deep within the lateral sulcus of the brain. Subdivisions within the insula have been identified on the basis of cytoarchitectonics, sulcal landmarks, and connectivity. Depending on the parcellation technique used, the insula can be divided into anywhere between 2 and 13 distinct subdivisions. The insula subserves a wide variety of functions in humans ranging from sensory and affective processing to high-level cognition. Here, we provide a concise summary of known structural and functional features of the human insular cortex with a focus on lesion case studies and recent neuroimaging evidence for considerable functional heterogeneity of this brain region.

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