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Khani B, Mardanian F, Fesharaki SJ. Omega-3 supplementation effects on polycystic ovary syndrome symptoms and metabolic syndrome. J Res Med Sci. 2017;22:64doi: 10.4103/jrms.JRMS_644_16.
Khani, B., Mardanian, F., & Fesharaki, S. J. (2017). Omega-3 supplementation effects on polycystic ovary syndrome symptoms and metabolic syndrome. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2264. https://doi.org/10.4103/jrms.JRMS_644_16
Khani, Behnaz, et al. "Omega-3 supplementation effects on polycystic ovary syndrome symptoms and metabolic syndrome." Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences vol. 22 (2017): 64. doi: https://doi.org/10.4103/jrms.JRMS_644_16
Khani B, Mardanian F, Fesharaki SJ. Omega-3 supplementation effects on polycystic ovary syndrome symptoms and metabolic syndrome. J Res Med Sci. 2017 May 30;22:64. doi: 10.4103/jrms.JRMS_644_16. eCollection 2017. PMID: 28616051; PMCID: PMC5461594.
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J Res Med Sci. 2017 May 30;22:64. doi: 10.4103/jrms.JRMS_644_16. eCollection 2017.

Omega-3 supplementation effects on polycystic ovary syndrome symptoms and metabolic syndrome.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Behnaz Khani, Farahnaz Mardanian, Sajadeh Jafari Fesharaki

Affiliations

  1. Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
  2. Department of Obstetrics and Gynecology, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

PMID: 28616051 PMCID: PMC5461594 DOI: 10.4103/jrms.JRMS_644_16

Abstract

BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder with unknown etiology and with different complications. The aim of this study was to evaluate the effect of omega-3 supplementation on PCOS symptoms and metabolic syndrome.

MATERIALS AND METHODS: This double-blind clinical trial was performed in 2015 in Alzahra and Shahid Beheshti Hospitals, Isfahan, Iran, on 88 patients with PCOS. Intervention group took omega-3 supplements with dose of 2 g/day for 6 months (two capsules), but control group received two olive oil capsules. Finally, ultrasound and laboratory findings and the recovery rate of menstrual disorders in both groups were compared.

RESULTS: After 6 months' intervention, waist circumference (WC) was significantly lower in omega-3 as compared to control (81.18 ± 2.87 vs. 84.22 ± 2.61 cm, respectively,

CONCLUSION: Omega-3 decrease lipid profiles, WC, and interval between periods while weight, hip circumference, fasting blood sugar, number of ovarian follicle, size of ovary, bleeding volume, menstrual bleeding, and hirsutism score did not change by administration of omega-3.

Keywords: Metabolic syndrome; omega-3; polycystic ovary syndrome

Conflict of interest statement

The authors have no conflicts of interest.

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