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Technol Cancer Res Treat. 2017 Dec;16(6):923-929. doi: 10.1177/1533034617710579. Epub 2017 May 30.

Characterization of Water-Clear Polymeric Gels for Use as Radiotherapy Bolus.

Technology in cancer research & treatment

Justus D Adamson, Tabitha Cooney, Farokh Demehri, Andrew Stalnecker, Debra Georgas, Fang-Fang Yin, John Kirkpatrick

Affiliations

  1. Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA.
  2. Department of Neurology and Neurological Sciences, Division of Child Neurology, Stanford University, Stanford, CA, USA.
  3. University of Michigan, Ann Arbor, MI, USA.
  4. Fuqua School of Business, Duke University, Durham, NC, USA.

PMID: 28554255 PMCID: PMC5762050 DOI: 10.1177/1533034617710579

Abstract

Our purpose was to investigate polymeric gels for use as a highly transparent radiotherapy bolus and determine the relevant physical and dosimetric properties. We first quantified tensile properties (maximum stress, strain, and Young modulus) for various polymeric gels, along with a commercial bolus product in order to illustrate the wide variety of potential materials. For a select polymeric gel with tensile properties similar to currently used radiotherapy bolus, we also evaluated mass and electron density, effective atomic number, optical transparency, and percent depth dose in clinical megavoltage photon and electron beams. For this polymeric gel, mass density was 872 ± 12 and 896 ± 13 g/cm

Keywords: 3-D conformal radiotherapy; bolus; dosimetry; external beam radiation therapy; surface dose

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