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Clin Transl Med. 2017 Dec;6(1):31. doi: 10.1186/s40169-017-0161-6. Epub 2017 Aug 07.

Purified umbilical cord derived mesenchymal stem cell treatment in a case of systemic lupus erythematosus.

Clinical and translational medicine

Christopher D Phillips, Pornpatcharin Wongsaisri, Thein Htut, Terry Grossman

Affiliations

  1. Phillips Neurological Institute, LLC, P.O. Box 251, Las Marias, PR, 00670, USA. [email protected].
  2. IntelliHealth Plus Clinic, 53 Soi Ruamsudee, Ploenchit Rd. Lumpini, Pathunam, Bangkok, 10330, Thailand.
  3. Grossman Wellness Center, 2801 Youngfield St. #117, Golden, CO, 80401, USA.
  4. Bumrungrad International Hospital, 33 Soi Sukhumvit 3, Klongtoey Nua, Wattana, Bangkok, 10110, Thailand.

PMID: 28782090 DOI: 10.1186/s40169-017-0161-6

Abstract

INTRODUCTION: Systemic lupus erythematosus (SLE) is a multiple organ system autoimmune disorder for which there is no known cure.

METHODS: We report a case of a young adult lady with SLE and Sjogren's with diagnostic and clinical resolution following purified umbilical cord derived mesenchymal stem cell (MSC) and globulin component protein macrophage activating factor (GcMAF) therapy in a combined multidisciplinary integrative medicine protocol.

RESULTS: Our patient had complete reversal of all clinical and laboratory markers.

CONCLUSION: We recommend a prospective randomized double blind study to assess the sustained efficacy of MSC and GcMAF in the treatment of autoimmune connective tissue diseases such as systemic lupus erythematosus.

Keywords: Autoimmune diseases; Connective tissue diseases; Lupus; Mesenchymal stem cells; Sjogren’s; Systemic lupus erythematosus; Systemic sclerosis; gcMAF

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