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Chlebowski AC, La Du JK, Truong L, et al. Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing. Toxicol Rep. 2017;4:202-210doi: 10.1016/j.toxrep.2017.04.005.
Chlebowski, A. C., La Du, J. K., Truong, L., Massey Simonich, S. L., & Tanguay, R. L. (2017). Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing. Toxicology reports, 4202-210. https://doi.org/10.1016/j.toxrep.2017.04.005
Chlebowski, Anna C, et al. "Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing." Toxicology reports vol. 4 (2017): 202-210. doi: https://doi.org/10.1016/j.toxrep.2017.04.005
Chlebowski AC, La Du JK, Truong L, Massey Simonich SL, Tanguay RL. Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing. Toxicol Rep. 2017;4:202-210. doi: 10.1016/j.toxrep.2017.04.005. Epub 2017 Apr 27. PMID: 28758069; PMCID: PMC5527975.
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Toxicol Rep. 2017;4:202-210. doi: 10.1016/j.toxrep.2017.04.005. Epub 2017 Apr 27.

Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing.

Toxicology reports

Anna C Chlebowski, Jane K La Du, Lisa Truong, Staci L Massey Simonich, Robert L Tanguay

Affiliations

  1. Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 97331.
  2. Department of Chemistry, Oregon State University, Corvallis, OR, 97331.

PMID: 28758069 PMCID: PMC5527975 DOI: 10.1016/j.toxrep.2017.04.005

Abstract

Nitroreductase enzymes are responsible for the reduction of nitro functional groups to amino functional groups, and are found in a range of animal models, zebrafish (

Keywords: nitrated polycyclic aromatic hydrocarbon; nitroreductase; pharmaceuticals; tissue ablation; transgenic; zebrafish

Conflict of interest statement

The authors declare no conflicts of interest.

References

  1. Environ Toxicol Chem. 2001 Jan;20(1):149-59 - PubMed
  2. Nat Rev Genet. 2001 Oct;2(10):743-55 - PubMed
  3. Arch Toxicol. 2002 Jun;76(5-6):287-98 - PubMed
  4. Toxicol Sci. 2002 Aug;68(2):403-19 - PubMed
  5. Mech Dev. 2003 Jan;120(1):5-18 - PubMed
  6. Am J Med. 1992 May;92(5):465-70 - PubMed
  7. Cancer Sci. 2004 Jan;95(1):1-6 - PubMed
  8. Trends Genet. 2004 Aug;20(8):384-91 - PubMed
  9. Environ Mol Mutagen. 2005 Mar-Apr;45(2-3):106-14 - PubMed
  10. Drug Metab Dispos. 2006 Jun;34(6):984-92 - PubMed
  11. Neurotoxicol Teratol. 2006 Jul-Aug;28(4):497-508 - PubMed
  12. Curr Drug Metab. 2006 Oct;7(7):715-27 - PubMed
  13. Mech Dev. 2007 Mar;124(3):218-29 - PubMed
  14. J Appl Toxicol. 2007 Jul-Aug;27(4):380-90 - PubMed
  15. Dev Dyn. 2007 Apr;236(4):1025-35 - PubMed
  16. Drug Metab Dispos. 2008 Jul;36(7):1425-37 - PubMed
  17. Nat Protoc. 2008;3(6):948-54 - PubMed
  18. J Appl Toxicol. 2009 Oct;29(7):597-602 - PubMed
  19. Mar Biotechnol (NY). 2010 Aug;12(4):466-78 - PubMed
  20. Toxicology. 2010 Sep 10;275(1-3):36-49 - PubMed
  21. Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17315-20 - PubMed
  22. Comp Biochem Physiol C Toxicol Pharmacol. 2011 Jan;153(1):91-8 - PubMed
  23. Methods Mol Biol. 2011;691:271-9 - PubMed
  24. Aquat Toxicol. 2011 Jan 17;101(1):165-74 - PubMed
  25. Dev Dyn. 2011 Aug;240(8):1929-37 - PubMed
  26. Reprod Toxicol. 2012 Apr;33(2):142-54 - PubMed
  27. Toxicol Appl Pharmacol. 2011 Dec 1;257(2):242-9 - PubMed
  28. Clin Neuropharmacol. 2011 Nov-Dec;34(6):241-7 - PubMed
  29. Reprod Toxicol. 2012 Apr;33(2):213-23 - PubMed
  30. PLoS One. 2012;7(1):e29346 - PubMed
  31. J Lab Autom. 2012 Feb;17(1):66-74 - PubMed
  32. Drug Metab Rev. 1990;22(2-3):209-68 - PubMed
  33. Methods. 2013 Aug 15;62(3):232-40 - PubMed
  34. Nature. 2013 Apr 25;496(7446):498-503 - PubMed
  35. Toxicol Appl Pharmacol. 2013 Sep 1;271(2):266-75 - PubMed
  36. Inflammopharmacology. 2013 Jun;21(3):201-32 - PubMed
  37. Toxicol Sci. 2014 Jan;137(1):212-33 - PubMed
  38. Gastroenterology. 2014 Mar;146(3):776-88 - PubMed
  39. Gastroenterology. 2014 Mar;146(3):789-800.e8 - PubMed
  40. Zebrafish. 2014 Apr;11(2):85-97 - PubMed
  41. Biosens Bioelectron. 2015 Jan 15;63:112-116 - PubMed
  42. Curr Environ Health Rep. 2014 Sep 7;1(4):341-352 - PubMed
  43. Pharmacol Ther. 2016 May;161:11-21 - PubMed
  44. Reprod Toxicol. 2016 Oct;65:139-147 - PubMed
  45. Neurotoxicol Teratol. 2017 Jan - Feb;59:27-34 - PubMed
  46. Toxicol Sci. 2017 May 1;157(1):246-259 - PubMed
  47. Environ Toxicol Chem. 1999 Oct;18(10):2268-2274 - PubMed
  48. Mutat Res. 1988 Nov-Dec;209(3-4):123-9 - PubMed
  49. J Pharmacol Exp Ther. 1973 Oct;187(1):185-94 - PubMed
  50. Surgery. 1983 Jan;93(1 Pt 2):158-64 - PubMed
  51. Annu Rev Med. 1984;35:577-93 - PubMed
  52. Mutat Res. 1984 Nov-Dec;138(2-3):113-25 - PubMed
  53. J Lab Clin Med. 1981 Jun;97(6):881-6 - PubMed
  54. J Urol. 1996 Jan;155(1):209-12 - PubMed
  55. Environ Health Perspect. 1994 Oct;102 Suppl 4:139-46 - PubMed
  56. J Pharmacol Exp Ther. 1993 Apr;265(1):366-72 - PubMed
  57. Dev Dyn. 1995 Jul;203(3):253-310 - PubMed
  58. Eur J Cancer. 1995 Dec;31A(13-14):2362-70 - PubMed
  59. Science. 1997 Apr 4;276(5309):60-6 - PubMed
  60. Drug Metab Dispos. 1997 Nov;25(11):1298-303 - PubMed
  61. Toxicol Appl Pharmacol. 1998 Sep;152(1):193-9 - PubMed

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