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Scavone M, Armentano I, Fortunati E, et al. Antimicrobial Properties and Cytocompatibility of PLGA/Ag Nanocomposites. Materials (Basel). 2016;9(1)doi: 10.3390/ma9010037.
Scavone, M., Armentano, I., Fortunati, E., Cristofaro, F., Mattioli, S., Torre, L., Kenny, J. M., Imbriani, M., Arciola, C. R., & Visai, L. (2016). Antimicrobial Properties and Cytocompatibility of PLGA/Ag Nanocomposites. Materials (Basel, Switzerland), 9(1), . https://doi.org/10.3390/ma9010037
Scavone, Mariangela, et al. "Antimicrobial Properties and Cytocompatibility of PLGA/Ag Nanocomposites." Materials (Basel, Switzerland) vol. 9,1 (2016). doi: https://doi.org/10.3390/ma9010037
Scavone M, Armentano I, Fortunati E, Cristofaro F, Mattioli S, Torre L, Kenny JM, Imbriani M, Arciola CR, Visai L. Antimicrobial Properties and Cytocompatibility of PLGA/Ag Nanocomposites. Materials (Basel). 2016 Jan 11;9(1). doi: 10.3390/ma9010037. PMID: 28787836; PMCID: PMC5456580.
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Materials (Basel). 2016 Jan 11;9(1). doi: 10.3390/ma9010037.

Antimicrobial Properties and Cytocompatibility of PLGA/Ag Nanocomposites.

Materials (Basel, Switzerland)

Mariangela Scavone, Ilaria Armentano, Elena Fortunati, Francesco Cristofaro, Samantha Mattioli, Luigi Torre, Jose M Kenny, Marcello Imbriani, Carla Renata Arciola, Livia Visai

Affiliations

  1. Unité Mixte de Recherche (UMR) S949, Inserm, Strasbourg 67000, France. [email protected].
  2. Etablissement Français du Sang-Alsace (EFS-Alsace), Strasbourg 67000, France. [email protected].
  3. Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg 67000, France. [email protected].
  4. Université de Strasbourg, Strasbourg 67000, France. [email protected].
  5. Materials Engineering Center, UdR INSTM, University of Perugia, Terni 05100, Italy. [email protected].
  6. Materials Engineering Center, UdR INSTM, University of Perugia, Terni 05100, Italy. [email protected].
  7. Department of Molecular Medicine, INSTM UdR of Pavia, Biochemistry Unit, "A Castellani", Viale Taramelli, 3/b-27100 Pavia, Center for Health Technologies (C.H.T.), University of Pavia, Pavia 27100, Italy. [email protected].
  8. Materials Engineering Center, UdR INSTM, University of Perugia, Terni 05100, Italy. [email protected].
  9. Materials Engineering Center, UdR INSTM, University of Perugia, Terni 05100, Italy. [email protected].
  10. Materials Engineering Center, UdR INSTM, University of Perugia, Terni 05100, Italy. [email protected].
  11. Department of Public Health, Experimental Medicine and Forensics, University of Pavia, Pavia 27100, Italy. [email protected].
  12. Department of Occupational Medicine, Toxicology and Environmental Risks, S. Maugeri Foundation, IRCCS Pavia 27100, Italy. [email protected].
  13. Research Unit on Implant Infections, Rizzoli Orthopaedic Institute, and DIMES, University of Bologna, Via di Barbiano 1/10-40136, Bologna, Italy. [email protected].
  14. Department of Molecular Medicine, INSTM UdR of Pavia, Biochemistry Unit, "A Castellani", Viale Taramelli, 3/b-27100 Pavia, Center for Health Technologies (C.H.T.), University of Pavia, Pavia 27100, Italy. [email protected].
  15. Department of Occupational Medicine, Toxicology and Environmental Risks, S. Maugeri Foundation, IRCCS Pavia 27100, Italy. [email protected].

PMID: 28787836 PMCID: PMC5456580 DOI: 10.3390/ma9010037

Abstract

The purpose of this study was to investigate the antimicrobial properties of multifunctional nanocomposites based on poly(dl-Lactide-co-Glycolide) (PLGA) and increasing concentration of silver (Ag) nanoparticles and their effects on cell viability for biomedical applications. PLGA nanocomposite films, produced by solvent casting with 1 wt%, 3 wt% and 7 wt% of Ag nanoparticles were investigated and surface properties were characterized by atomic force microscopy and contact angle measurements. Antibacterial tests were performed using an

Keywords: Ag nanocomposites; antibacterial activity; cell cytocompatibility

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