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Rev Gastroenterol Peru. 2017 Apr-Jun;37(2):146-155.

[Update on chronic pancreatitis: review article].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru

[Article in Spanish]
Frank Czul, Emmanuel Coronel, Jean A Donet

Affiliations

  1. Gastroenterology, Presbyterian Healthcare Services. Albuquerque, EE UU.
  2. Division of Gastroenterology, University of Chicago. Chicago, EE UU.
  3. Division of Gastroenterology, University of Miami Miller School of Medicine. Miami, EEUU.

PMID: 28731995

Abstract

Chronic pancreatitis is a progressive fibro-inflammatory disease of the pancreas characterized by irreversible fibrosis of the gland with eventual failure of exocrine and endocrine functions and hallmark features of abdominal pain, malabsorption, malnutrition, diabetes mellitus and pancreatic calcifications. In many patients this disease results from a complex mix of environmental (eg, alcohol, cigarettes, and occupational chemicals), genetic factors and a few patients with hereditary or autoimmune disease. The management includes medical, endoscopic and surgical approaches with the need for interaction between various specialties, calling for a concerted multidisciplinary approach. This review provides the reader with a comprehensive overview of the studies summarizing the epidemiology, etiology, physiopatology, clinical manifestation, diagnosis and treatments of the disease.

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