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Kotloff KL. The Burden and Etiology of Diarrheal Illness in Developing Countries. Pediatr Clin North Am. 2017;64(4):799-814doi: 10.1016/j.pcl.2017.03.006.
Kotloff, K. L. (2017). The Burden and Etiology of Diarrheal Illness in Developing Countries. Pediatric clinics of North America, 64(4), 799-814. https://doi.org/10.1016/j.pcl.2017.03.006
Kotloff, Karen L. "The Burden and Etiology of Diarrheal Illness in Developing Countries." Pediatric clinics of North America vol. 64,4 (2017): 799-814. doi: https://doi.org/10.1016/j.pcl.2017.03.006
Kotloff KL. The Burden and Etiology of Diarrheal Illness in Developing Countries. Pediatr Clin North Am. 2017 Aug;64(4):799-814. doi: 10.1016/j.pcl.2017.03.006. PMID: 28734511.
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Pediatr Clin North Am. 2017 Aug;64(4):799-814. doi: 10.1016/j.pcl.2017.03.006.

The Burden and Etiology of Diarrheal Illness in Developing Countries.

Pediatric clinics of North America

Karen L Kotloff

Affiliations

  1. Division of Infectious Disease and Tropical Pediatrics, Center for Vaccine Development, Institute for Global Health, University of Maryland School of Medicine, 685 West Baltimore Street, HSF 480, Baltimore, MD 21201, USA. Electronic address: [email protected].

PMID: 28734511 DOI: 10.1016/j.pcl.2017.03.006

Abstract

Reductions in mortality from diarrheal diseases among young children have occurred in recent decades; however, approximately 500,000 children continue to die each year. Moreover, similar reductions in disease incidence have not been seen, episodes that impact the growth and development of young children. Two recent studies, MAL-ED and GEMS, have more clearly defined the burden and cause of diarrhea among young children, identifying four leading pathogens: rotavirus, CryptosporidiumShigella, and heat stable toxin-producing enterotoxigenic Escherichia coli. Global introduction of rotavirus vaccine is poised to substantially reduce the incidence of rotavirus infection. Interventions are needed to reduce the burden that remains.

Copyright © 2017 Elsevier Inc. All rights reserved.

Keywords: Burden; Cryptosporidium; Developing countries; Diarrhea; ETEC; Gastroenteritis; Rotavirus; Shigella

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