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Mathews MA, Camp AJ, Murray AJ. Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits. Front Physiol. 2017;8:552doi: 10.3389/fphys.2017.00552.
Mathews, M. A., Camp, A. J., & Murray, A. J. (2017). Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits. Frontiers in physiology, 8552. https://doi.org/10.3389/fphys.2017.00552
Mathews, Miranda A, et al. "Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits." Frontiers in physiology vol. 8 (2017): 552. doi: https://doi.org/10.3389/fphys.2017.00552
Mathews MA, Camp AJ, Murray AJ. Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits. Front Physiol. 2017 Aug 02;8:552. doi: 10.3389/fphys.2017.00552. eCollection 2017. PMID: 28824449; PMCID: PMC5539236.
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Front Physiol. 2017 Aug 02;8:552. doi: 10.3389/fphys.2017.00552. eCollection 2017.

Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits.

Frontiers in physiology

Miranda A Mathews, Aaron J Camp, Andrew J Murray

Affiliations

  1. Sensory Systems and Integration Laboratory, Bosch Institute, Discipline of Biomedical Science, University of SydneySydney, NSW, Australia.
  2. Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College LondonLondon, United Kingdom.

PMID: 28824449 PMCID: PMC5539236 DOI: 10.3389/fphys.2017.00552

Abstract

Efferent circuits within the nervous system carry nerve impulses from the central nervous system to sensory end organs. Vestibular efferents originate in the brainstem and terminate on hair cells and primary afferent fibers in the semicircular canals and otolith organs within the inner ear. The function of this efferent vestibular system (EVS) in vestibular and motor coordination though, has proven difficult to determine, and remains under debate. We consider current literature that implicate corollary discharge from the spinal cord through the efferent vestibular nucleus (EVN), and hint at a potential role in overall vestibular plasticity and compensation. Hypotheses range from differentiating between passive and active movements at the level of vestibular afferents, to EVS activation under specific behavioral and environmental contexts such as arousal, predation, and locomotion. In this review, we summarize current knowledge of EVS circuitry, its effects on vestibular hair cell and primary afferent activity, and discuss its potential functional roles.

Keywords: EVN; EVS; VOR; corollary discharge; efferent vestibular nucleus; efferent vestibular system; vestibular; vestibular plasticity

References

  1. J Neurophysiol. 2002 Sep;88(3):1234-44 - PubMed
  2. eNeuro. 2015 Dec 26;2(6):null - PubMed
  3. Acta Otolaryngol. 1993 May;113(3):229-34 - PubMed
  4. J Neurophysiol. 2006 Jun;95(6):3297-308 - PubMed
  5. J Neurosci. 2014 Jun 11;34(24):8347-57 - PubMed
  6. J Comp Neurol. 1988 Nov 8;277(2):234-49 - PubMed
  7. Brain Res. 1991 Dec 6;566(1-2):103-7 - PubMed
  8. J Neurosci. 2014 Jul 30;34(31):10453-8 - PubMed
  9. Curr Opin Otolaryngol Head Neck Surg. 2010 Oct;18(5):447-53 - PubMed
  10. J Neurophysiol. 2009 Jan;101(1):141-9 - PubMed
  11. J Biol Chem. 2013 Mar 29;288(13):9334-44 - PubMed
  12. Neirofiziologiia. 1986;18(6):738-47 - PubMed
  13. Acta Biol Hung. 1988;39(2-3):229-49 - PubMed
  14. J Neurophysiol. 1997 Apr;77(4):2061-70 - PubMed
  15. J Physiol. 1984 Nov;356:525-50 - PubMed
  16. Neuroscience. 1995 Nov;69(2):661-9 - PubMed
  17. Neurosci Lett. 1981 Dec 23;27(3):231-5 - PubMed
  18. Nat Commun. 2015 Sep 04;6:7982 - PubMed
  19. Brain Res. 2004 Dec 3;1028(2):140-7 - PubMed
  20. Nat Neurosci. 2011 Apr;14(4):527-32 - PubMed
  21. Neuroscience. 1994 Oct;62(3):963-74 - PubMed
  22. PLoS One. 2014 May 27;9(5):e98277 - PubMed
  23. J Neurophysiol. 2005 Jan;93(1):251-66 - PubMed
  24. Exp Brain Res. 1976 Mar 15;24(5):447-57 - PubMed
  25. J Physiol. 1994 Jul 1;478 ( Pt 1):17-35 - PubMed
  26. J Anat. 2015 Aug;227(2):157-66 - PubMed
  27. Int J Biomed Sci. 2010 Dec;6(4):276-88 - PubMed
  28. J Commun Disord. 1998 Nov-Dec;31(6):471-82; quiz 483; 553 - PubMed
  29. J Neurophysiol. 1980 May;43(5):1426-36 - PubMed
  30. Curr Opin Neurol. 2002 Feb;15(1):11-5 - PubMed
  31. Exp Brain Res. 1989;78(2):315-26 - PubMed
  32. J Physiol. 2015 May 15;593(10):2389-98 - PubMed
  33. Doc Ophthalmol. 2017 Feb;134(1):57-73 - PubMed
  34. Methods. 2015 Nov 15;90:28-38 - PubMed
  35. J Comp Neurol. 1987 Nov 22;265(4):494-506 - PubMed
  36. Exp Brain Res. 1976 Jun 30;25(4):369-90 - PubMed
  37. J Neurophysiol. 2000 Mar;83(3):1224-42 - PubMed
  38. Neurosci Lett. 1981 Nov 4;26(3):191-6 - PubMed
  39. Neuroscience. 2010 Sep 29;170(1):348-60 - PubMed
  40. Brain Res. 1986 Jan 1;362(1):92-7 - PubMed
  41. Neuroreport. 1997 May 6;8(7):1779-83 - PubMed
  42. J Neurophysiol. 2009 Feb;101(2):988-1001 - PubMed
  43. Exp Brain Res. 1971 Oct 25;13(4):378-407 - PubMed
  44. Exp Brain Res. 1994;99(3):441-54 - PubMed
  45. J Neurosci. 2017 Feb 15;37(7):1873-1887 - PubMed
  46. Exp Brain Res. 2006 May;171(2):251-61 - PubMed
  47. Brain Res. 1980 Mar 3;185(1):125-37 - PubMed
  48. Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1665-70 - PubMed
  49. Neurosci Res. 1991 Oct;12(1):13-30 - PubMed
  50. J Assoc Res Otolaryngol. 2004 Jun;5(2):126-43 - PubMed
  51. Trends Neurosci. 2009 Jan;32(1):19-29 - PubMed
  52. Front Neurol. 2012 Feb 28;3:4 - PubMed
  53. Arch Otorhinolaryngol. 1982;234(2):139-43 - PubMed
  54. PLoS One. 2010 Oct 29;5(10):e13777 - PubMed
  55. Neuroscience. 1993 Dec;57(4):1097-108 - PubMed
  56. J Neurophysiol. 2015 Dec;114(6):3154-65 - PubMed
  57. PLoS One. 2015 Sep 30;10(9):e0139548 - PubMed
  58. Pflugers Arch. 1968;304(2):183-8 - PubMed
  59. J Neurophysiol. 1993 Dec;70(6):2533-49 - PubMed
  60. J Neurophysiol. 2004 May;91(5):1919-33 - PubMed
  61. J Neurophysiol. 2003 Sep;90(3):1526-36 - PubMed
  62. Pflugers Arch. 1970;318(4):325-32 - PubMed
  63. Nat Neurosci. 2002 Jan;5(1):57-63 - PubMed
  64. Am J Physiol. 1997 Sep;273(3 Pt 2):R1142-6 - PubMed
  65. Hear Res. 1994 May;75(1-2):225-32 - PubMed
  66. Hear Res. 1990 Jan;43(2-3):121-33 - PubMed
  67. Hear Res. 1992 Aug;61(1-2):56-64 - PubMed
  68. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3864-9 - PubMed
  69. Front Neuroinform. 2014 Feb 05;8:5 - PubMed
  70. Prog Brain Res. 2005;149:107-26 - PubMed
  71. J Neurophysiol. 2009 Sep;102(3):1513-25 - PubMed
  72. Nat Rev Neurosci. 2010 May;11(5):316-28 - PubMed
  73. Acta Otolaryngol. 1982 Sep-Oct;94(3-4):299-305 - PubMed
  74. J Neurosci. 2015 Feb 25;35(8):3625-43 - PubMed
  75. Annu Rev Neurosci. 2008;31:125-50 - PubMed
  76. Jpn J Physiol. 1991;41(2):217-32 - PubMed
  77. Curr Opin Neurobiol. 2004 Dec;14(6):698-706 - PubMed
  78. Brain Res. 2011 Feb 10;1373:25-38 - PubMed
  79. Cell. 1994 Nov 18;79(4):705-15 - PubMed
  80. Ear Hear. 2006 Dec;27(6):589-607 - PubMed
  81. Pflugers Arch. 1980 Nov;388(2):123-8 - PubMed
  82. Neurosci Lett. 2015 Aug 18;602:156-61 - PubMed
  83. Brain Res. 1985 Sep 30;344(1):1-8 - PubMed
  84. J Neurosci. 2006 Dec 20;26(51):13180-93 - PubMed
  85. Nat Neurosci. 2006 Dec;9(12):1474-6 - PubMed
  86. J Comp Neurol. 1989 Feb 22;280(4):663-71 - PubMed
  87. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3501-6 - PubMed
  88. J Neurophysiol. 2014 Aug 15;112(4):870-89 - PubMed
  89. J Neurophysiol. 1994 Jun;71(6):2087-92 - PubMed
  90. Science. 1985 Apr 12;228(4696):199-202 - PubMed
  91. Acta Otolaryngol. 1962 Sep;55:205-17 - PubMed
  92. Acta Otolaryngol. 1986 Sep-Oct;102(3-4):194-203 - PubMed
  93. Annu Rev Neurosci. 2008;31:317-38 - PubMed
  94. Neuroscience. 2011 Feb 23;175:104-17 - PubMed
  95. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):17078-82 - PubMed
  96. J Physiol. 2005 Jul 1;566(Pt 1):49-59 - PubMed
  97. Osaka City Med J. 1996 Dec;42(2):61-76 - PubMed
  98. Exp Brain Res. 2000 Oct;134(3):402-6 - PubMed
  99. Brain Behav Evol. 1996;47(4):185-94 - PubMed
  100. J Neurobiol. 2002 Nov 5;53(2):228-50 - PubMed
  101. J Comp Neurol. 1997 Dec 22;389(3):419-43 - PubMed
  102. Hear Res. 1988 Feb-Mar;32(2-3):197-206 - PubMed
  103. Brain Behav Evol. 1984;24(2-3):135-43 - PubMed
  104. Neuroscience. 2003;118(1):75-85 - PubMed
  105. Brain Res Bull. 2000 Sep 1;53(1):11-6 - PubMed
  106. Neuroscience. 1999;93(2):801-6 - PubMed
  107. Brain Res. 2001 Dec 7;921(1-2):44-59 - PubMed
  108. Neurosci Lett. 1989 Jan 30;96(3):241-6 - PubMed
  109. Exp Brain Res. 1986;64(1):19-26 - PubMed
  110. J Neurosci. 1990 May;10(5):1570-82 - PubMed
  111. Exp Brain Res. 2011 May;210(3-4):377-88 - PubMed
  112. Brain Res. 1989 Dec 11;504(1):31-5 - PubMed
  113. J Comp Neurol. 2014 Jun 1;522(8):1728-52 - PubMed
  114. J Vestib Res. 2005;15(3):119-29 - PubMed
  115. Int J Mol Sci. 2013 Apr 24;14(5):8818-31 - PubMed
  116. J Neurophysiol. 2006 May;95(5):3208-18 - PubMed
  117. J Assoc Res Otolaryngol. 2005 Dec;6(4):311-23 - PubMed
  118. Neurosci Lett. 1993 Oct 1;160(2):185-9 - PubMed
  119. J Neurophysiol. 2017 Feb 1;117(2):604-611 - PubMed
  120. Hear Res. 1994 May;75(1-2):191-200 - PubMed
  121. J Neurophysiol. 2006 Jun;95(6):3562-70 - PubMed
  122. Neurosci Lett. 1981 Sep 25;25(3):239-42 - PubMed
  123. J Neurosci. 1994 Oct;14(10):6071-83 - PubMed
  124. J Neurophysiol. 2017 Apr 1;117(4):1553-1568 - PubMed
  125. J Comp Neurol. 1975 May 15;161(2):159-81 - PubMed
  126. Hear Res. 2002 May;167(1-2):122-35 - PubMed
  127. Ann N Y Acad Sci. 1992 May 22;656:108-23 - PubMed
  128. Hear Res. 2001 Feb;152(1-2):25-42 - PubMed
  129. J Comp Neurol. 2014 Jun 15;522(9):2053-74 - PubMed
  130. Dev Biol. 2003 Aug 1;260(1):46-57 - PubMed
  131. Neuroscience. 1995 Feb;64(4):1153-60 - PubMed
  132. Neurosci Lett. 1981 Dec 11;27(2):95-100 - PubMed
  133. Acta Otolaryngol. 1982 Jul-Aug;94(1-2):45-51 - PubMed
  134. J Neurophysiol. 2007 Feb;97(2):1503-14 - PubMed
  135. Acta Otolaryngol. 1963 Feb;56:51-64 - PubMed
  136. Hear Res. 1990 Nov;49(1-3):89-102 - PubMed
  137. Otolaryngol Head Neck Surg. 1991 Oct;105(4):493-510 - PubMed
  138. Otolaryngol Head Neck Surg. 1994 Oct;111(4):385-95 - PubMed
  139. J Neurophysiol. 2016 Feb 1;115(2):833-42 - PubMed
  140. J Vestib Res. 2013;23(3):161-75 - PubMed
  141. J Neurophysiol. 2012 Mar;107(5):1301-12 - PubMed
  142. J Neurophysiol. 1991 Nov;66(5):1504-21 - PubMed
  143. Front Neuroanat. 2016 Feb 08;10:7 - PubMed
  144. Prog Neurobiol. 2004 Jul;73(4):259-309 - PubMed
  145. J Neurophysiol. 1993 Dec;70(6):2519-32 - PubMed
  146. J Neurosci. 2002 Jun 1;22(11):RC226 - PubMed
  147. J Neurophysiol. 1980 Apr;43(4):986-1025 - PubMed
  148. Brain Res. 1985 Jul 15;338(2):225-36 - PubMed
  149. J Neurophysiol. 2003 Jul;90(1):184-203 - PubMed
  150. J Physiol. 1979 Jun;291:277-90 - PubMed
  151. J Physiol. 1981 Jun;315:203-15 - PubMed
  152. Neuron. 2000 Jun;26(3):595-601 - PubMed
  153. Brain Res. 1997 Dec 19;778(2):409-13 - PubMed
  154. Curr Opin Neurobiol. 2008 Dec;18(6):552-7 - PubMed
  155. J Neurophysiol. 1985 Aug;54(2):370-84 - PubMed
  156. Neurosci Lett. 1984 May 4;46(2):131-6 - PubMed
  157. Exp Brain Res. 2002 Apr;143(4):463-9 - PubMed
  158. J Comp Neurol. 1986 Jan 15;243(3):309-25 - PubMed
  159. J Comp Neurol. 2000 Nov 27;427(4):508-21 - PubMed
  160. Exp Brain Res. 2006 Jun;172(2):261-74 - PubMed
  161. J Neurophysiol. 1997 May;77(5):2788-804 - PubMed
  162. J Neurophysiol. 2001 Mar;85(3):1107-18 - PubMed
  163. Brain Res. 1996 Nov 4;738(2):347-52 - PubMed

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