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Jpn J Radiol. 2017 Oct;35(10):555-561. doi: 10.1007/s11604-017-0671-6. Epub 2017 Aug 09.

Capacity of gold nanoparticles in cancer radiotherapy.

Japanese journal of radiology

Nadeem M S Nagi, Yasir A M Khair, Ahmed M E Abdalla

Affiliations

  1. Department of Oncology, King Khaled Hospital, King Abdulaziz Road, Najran, 61441, Saudi Arabia.
  2. Department of Biochemistry and Molecular Biology, College of Applied Science, University of Bahri, Bahri El-Ingaz Street, West Railway, P.O Box 1660, 11111, Khartoum, Sudan. [email protected].

PMID: 28795273 DOI: 10.1007/s11604-017-0671-6

Abstract

Radiotherapy is the ionizing radiation used for treatment of cancer and other diseases. Although radiotherapy is the major treatment for cancer, a lot of patients do not undergo radiation due to associated risks such as radiation pneumonitis, cardiovascular complications, development of secondary tumor, and lymphedema. However, the advantages of nanotechnology provide a unique potential to enhance radiotherapeutic performance, in particular by utilizing gold nanoparticles (Au NPs). In this review, we briefly describe the current direction of research towards the use of Au NPs for radiotherapeutic enhancement, combination, monitoring and in side effect reductions.

Keywords: Cancer radiotherapy; Drug resistance; Gold nanoparticles; Radio-sensitizer

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