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Fowler ME, Akinyemiju TF. Meta-analysis of the association between dietary inflammatory index (DII) and cancer outcomes. Int J Cancer. 2017;141(11):2215-2227doi: 10.1002/ijc.30922.
Fowler, M. E., & Akinyemiju, T. F. (2017). Meta-analysis of the association between dietary inflammatory index (DII) and cancer outcomes. International journal of cancer, 141(11), 2215-2227. https://doi.org/10.1002/ijc.30922
Fowler, Mackenzie E, and Akinyemiju, Tomi F. "Meta-analysis of the association between dietary inflammatory index (DII) and cancer outcomes." International journal of cancer vol. 141,11 (2017): 2215-2227. doi: https://doi.org/10.1002/ijc.30922
Fowler ME, Akinyemiju TF. Meta-analysis of the association between dietary inflammatory index (DII) and cancer outcomes. Int J Cancer. 2017 Dec 01;141(11):2215-2227. doi: 10.1002/ijc.30922. Epub 2017 Aug 26. PMID: 28795402; PMCID: PMC6056732.
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Int J Cancer. 2017 Dec 01;141(11):2215-2227. doi: 10.1002/ijc.30922. Epub 2017 Aug 26.

Meta-analysis of the association between dietary inflammatory index (DII) and cancer outcomes.

International journal of cancer

Mackenzie E Fowler, Tomi F Akinyemiju

Affiliations

  1. Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL.
  2. Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL.
  3. Department of Epidemiology, University of Kentucky, Lexington, KY.

PMID: 28795402 PMCID: PMC6056732 DOI: 10.1002/ijc.30922

Abstract

Proinflammatory dietary patterns have been associated with increased cancer risk and mortality. We present a systematic review and meta-analysis of the current published literature on a dietary inflammatory index (DII) score and its association with cancer risk and mortality outcomes. Published articles from online databases (PubMed, Scopus, and Embase) examining the association between DII and any cancer risk, incidence, or mortality between 1980 and November 2016 were selected for review. Results of studies meeting inclusion criteria were summarized and meta-analyzed using STATA to generate summary measures of association across studies. Sixty-three published articles were identified from the search, and following title, abstract and full-text review, twenty-four studies met inclusion criteria. All articles calculated DII scores based on study-specific food-frequency questionnaires using methodology from the same article. Of the 24 included studies, 13 were case-control, 6 were prospective cohort, 1 was a retrospective cohort, 3 were RCTs, and 1 did not specify study design. The most common cancers examined were colorectal, breast, lung, and prostate. Individuals in the highest versus lowest DII categories had 25% increased risk of overall cancer incidence (RR: 1.25, 95% CI: 1.16-1.35), 75% higher odds of cancer (OR: 1.75, 95% CI: 1.43-2.16) and 67% increased risk of cancer mortality (RR: 1.67, 95% CI: 1.13-2.48). Upon stratification for cancer type, positive associations remained (RR

© 2017 UICC.

Keywords: cancer incidence; cancer mortality; diet; dietary inflammatory index; pro-inflammatory diet

References

  1. Cancer Epidemiol Biomarkers Prev. 2014 Nov;23(11):2383-92 - PubMed
  2. Cancer Epidemiol Biomarkers Prev. 2005 Dec;14(12):2826-8 - PubMed
  3. Nutrients. 2015 Apr 09;7(4):2589-621 - PubMed
  4. Cancer Causes Control. 2015 Oct;26(10):1439-47 - PubMed
  5. Urology. 2017 Feb;100:84-89 - PubMed
  6. J Biomed Biotechnol. 2012;2012:623019 - PubMed
  7. Nutr Cancer. 2016 Nov-Dec;68(8):1262-1268 - PubMed
  8. Br J Nutr. 2015 Jan 28;113(2):278-83 - PubMed
  9. Br J Nutr. 2015 Jun 14;113(11):1819-27 - PubMed
  10. Nutr Cancer. 2015;67(8):1253-9 - PubMed
  11. Mol Nutr Food Res. 2017 May;61(5): - PubMed
  12. J Clin Oncol. 2016 Sep 6;: - PubMed
  13. Nutrients. 2016 Jul 30;8(8): - PubMed
  14. Int J Cancer. 2016 Dec 1;139(11):2398-404 - PubMed
  15. Br J Nutr. 2016 Jan 14;115(1):138-46 - PubMed
  16. Cancer J. 2014 May-Jun;20(3):181-9 - PubMed
  17. Epigenomics. 2016 Aug;8(8):1019-37 - PubMed
  18. J Am Coll Cardiol. 2006 Aug 15;48(4):677-85 - PubMed
  19. J Nutr. 2009 Dec;139(12):2365-72 - PubMed
  20. Br J Nutr. 2015 Jan 28;113(2):292-8 - PubMed
  21. Eur J Nutr. 2016 Apr;55(3):1069-79 - PubMed
  22. Int J Cancer. 2017 Feb 1;140(3):535-543 - PubMed
  23. Genes Nutr. 2015 Jan;10(1):447 - PubMed
  24. Adv Nutr. 2017 Mar 15;8(2):213-225 - PubMed
  25. Mol Nutr Food Res. 2017 Mar;61(3): - PubMed
  26. Nutr Cancer. 2015;67(6):941-8 - PubMed
  27. Cancer Causes Control. 2016 Jul;27(7):907-17 - PubMed
  28. Am J Epidemiol. 1988 Jan;127(1):188-99 - PubMed
  29. J Nutr. 2016 Mar 9;146(4):785-791 - PubMed
  30. Am J Epidemiol. 2013 Jan 1;177(1):3-13 - PubMed
  31. Am J Clin Nutr. 2016 Mar;103(3):878-85 - PubMed
  32. Nutr Clin Pract. 2010 Dec;25(6):634-40 - PubMed
  33. Br J Cancer. 2015 Sep 29;113(7):1099-103 - PubMed
  34. Public Health Nutr. 2014 Aug;17(8):1689-96 - PubMed
  35. Cancer Causes Control. 2016 Jul;27(7):897-906 - PubMed
  36. Cancer Causes Control. 2015 Mar;26(3):399-408 - PubMed
  37. Clin Epigenetics. 2015 Oct 16;7:112 - PubMed

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