Display options
Cite
Thanh NTL, Vy NHT, Xuyen HTA, et al. No Evidence of On-farm Circulation of Avian Influenza H5 Subtype in Ca Mau Province, Southern Vietnam, March 2016 - January 2017. PLoS Curr. 2017;9doi: 10.1371/currents.outbreaks.c816d7333370d68f8a0da33f69168986.
Thanh, N. T. L., Vy, N. H. T., Xuyen, H. T. A., Phuong, H. T., Tuyet, P. N., Huy, N. T., Nguyen-Van-Yen, B., Lam, H. M., & Boni, M. F. (2017). No Evidence of On-farm Circulation of Avian Influenza H5 Subtype in Ca Mau Province, Southern Vietnam, March 2016 - January 2017. PLoS currents, 9. https://doi.org/10.1371/currents.outbreaks.c816d7333370d68f8a0da33f69168986
Thanh, Nguyen Thi Le, et al. "No Evidence of On-farm Circulation of Avian Influenza H5 Subtype in Ca Mau Province, Southern Vietnam, March 2016 - January 2017." PLoS currents vol. 9 (2017). doi: https://doi.org/10.1371/currents.outbreaks.c816d7333370d68f8a0da33f69168986
Thanh NTL, Vy NHT, Xuyen HTA, Phuong HT, Tuyet PN, Huy NT, Nguyen-Van-Yen B, Lam HM, Boni MF. No Evidence of On-farm Circulation of Avian Influenza H5 Subtype in Ca Mau Province, Southern Vietnam, March 2016 - January 2017. PLoS Curr. 2017 May 05;9. doi: 10.1371/currents.outbreaks.c816d7333370d68f8a0da33f69168986. PMID: 28736677; PMCID: PMC5501696.
Copy Download .nbib Format: NLM
Share it on

PLoS Curr. 2017 May 05;9. doi: 10.1371/currents.outbreaks.c816d7333370d68f8a0da33f69168986.

No Evidence of On-farm Circulation of Avian Influenza H5 Subtype in Ca Mau Province, Southern Vietnam, March 2016 - January 2017.

PLoS currents

Nguyen Thi Le Thanh, Nguyen Ha Thao Vy, Huynh Thi Ai Xuyen, Huynh Thi Phuong, Phung Ngoc Tuyet, Nguyen Thanh Huy, Benjamin Nguyen-Van-Yen, Ha Minh Lam, Maciej F Boni

Affiliations

  1. Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.
  2. Ca Mau sub-Department of Livestock Prodution and Animal Health, Ward 5, Ca Mau City, Ca Mau, Vietnam.
  3. Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam; Department of Biology, École Normale Supérieure, Paris, France.
  4. Department of Biology, Pennsylvania State University, University Park, PA, USA; Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, Vietnam.

PMID: 28736677 PMCID: PMC5501696 DOI: 10.1371/currents.outbreaks.c816d7333370d68f8a0da33f69168986

Abstract

BACKGROUND: Subtype H5N1 avian influenza viruses, both high pathogenicity and low pathogenicity, have been enzootic in Vietnam since 2001.  The viruses are readily identified at live bird markets, but virus prevalence on smallholder poultry is typically zero or very low.  If the true direction of the viral transmission chain is farm to market, it is unknown why farm prevalence should be low when market prevalence is moderate to high.

METHODS: We established a cohort of 50 smallholder poultry farms in Ca Mau province in the Mekong Delta region of Vietnam.  From March 2016 to January 2017, we collected naso-pharyngeal and cloacal samples from 156 ducks and 96 chickens.  In addition, 126 environmental samples were collected.  Samples were assayed for H5 subtype influenza by real-time RT-PCR. Results/Discussion: None of the 378 collected samples were positive for H5 influenza.  This is likely to mean that circulation of subtype H5 influenza viruses was low in Ca Mau in 2016.  Detection of avian influenza on smallholder poultry farms is necessary to determine the directionality and association between farm prevalence and market prevalence of avian influenza viruses.  Larger farm-level studies should be planned as these will be critical for determining the presence and strength of this association.

References

  1. J Virol. 2015 Sep;89(17):8671-6 - PubMed
  2. PLoS One. 2012;7(11):e50959 - PubMed
  3. PLoS One. 2014 May 02;9(5):e95015 - PubMed
  4. PLoS One. 2008;3(10):e3462 - PubMed
  5. Ecohealth. 2015 Dec;12 (4):726-35 - PubMed
  6. Nature. 2004 Jul 8;430(6996):209-13 - PubMed
  7. Sci Rep. 2015 Jan 15;5:7630 - PubMed
  8. Proc Natl Acad Sci U S A. 2004 May 25;101(21):8156-61 - PubMed
  9. Prev Vet Med. 2011 Sep 1;101(3-4):229-40 - PubMed
  10. Virology. 2013 Sep;444(1-2):12-20 - PubMed
  11. Transbound Emerg Dis. 2016 Apr;63(2):127-35 - PubMed
  12. N Engl J Med. 2014 Feb 6;370(6):520-32 - PubMed
  13. Virology. 2012 Oct 25;432(2):405-16 - PubMed
  14. Lancet. 2014 Feb 8;383(9916):541-8 - PubMed
  15. Emerg Infect Dis. 2014 Nov;20(11):1902-5 - PubMed
  16. Sci Rep. 2016 Jul 12;6:29463 - PubMed
  17. Zoonoses Public Health. 2016 Mar;63(2):112-28 - PubMed
  18. Transbound Emerg Dis. 2011 Dec;58(6):537-43 - PubMed
  19. Virus Genes. 2013 Oct;47(2):317-29 - PubMed
  20. Acta Trop. 2015 Jul;147:38-44 - PubMed
  21. Emerg Infect Dis. 2008 Apr;14(4):632-6 - PubMed
  22. PLoS One. 2012;7(6):e37986 - PubMed
  23. Spat Spatiotemporal Epidemiol. 2011 Mar;2(1):49-57 - PubMed
  24. Epidemiol Infect. 2013 Mar;141(3):601-11 - PubMed

Publication Types