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Piontek K, Schmidt CO, Baumeister SE, et al. Is hepatic steatosis associated with left ventricular mass index increase in the general population?. World J Hepatol. 2017;9(19):857-866doi: 10.4254/wjh.v9.i19.857.
Piontek, K., Schmidt, C. O., Baumeister, S. E., Lerch, M. M., Mayerle, J., Dörr, M., Felix, S. B., & Völzke, H. (2017). Is hepatic steatosis associated with left ventricular mass index increase in the general population?. World journal of hepatology, 9(19), 857-866. https://doi.org/10.4254/wjh.v9.i19.857
Piontek, Katharina, et al. "Is hepatic steatosis associated with left ventricular mass index increase in the general population?." World journal of hepatology vol. 9,19 (2017): 857-866. doi: https://doi.org/10.4254/wjh.v9.i19.857
Piontek K, Schmidt CO, Baumeister SE, Lerch MM, Mayerle J, Dörr M, Felix SB, Völzke H. Is hepatic steatosis associated with left ventricular mass index increase in the general population?. World J Hepatol. 2017 Jul 08;9(19):857-866. doi: 10.4254/wjh.v9.i19.857. PMID: 28740597; PMCID: PMC5504361.
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World J Hepatol. 2017 Jul 08;9(19):857-866. doi: 10.4254/wjh.v9.i19.857.

Is hepatic steatosis associated with left ventricular mass index increase in the general population?.

World journal of hepatology

Katharina Piontek, Carsten O Schmidt, Sebastian E Baumeister, Markus M Lerch, Julia Mayerle, Marcus Dörr, Stephan B Felix, Henry Völzke

Affiliations

  1. Katharina Piontek, Institute for Medical Psychology, University Medicine Greifswald, 17489 Greifswald, Germany.

PMID: 28740597 PMCID: PMC5504361 DOI: 10.4254/wjh.v9.i19.857

Abstract

AIM: To investigate the association between hepatic steatosis and change in left ventricular mass index (LVMI) over five years, and examine whether systolic and diastolic blood pressures are mediators of the association between hepatic steatosis and LVMI using a general population sample.

METHODS: We analyzed data from the Study of Health in Pomerania. The study population comprised 1298 individuals aged 45 to 81 years. Hepatic steatosis was defined as the presence of a hyperechogenic pattern of the liver together with elevated serum alanine transferase levels. Left ventricular mass was determined echocardiographically and indexed to height

RESULTS: Hepatic steatosis was a significant predictor for all measured echocardiographic characteristics at baseline. Path analyses revealed that the association of hepatic steatosis with LVMI change after five years was negligibly small (β = -0.12, s.e. = 0.21,

CONCLUSION: Baseline associations between hepatic steatosis and LVMI do not extend to associations with LVMI change after five years. More studies are needed to study the longitudinal effects of hepatic steatosis on LVMI.

Keywords: Blood pressure; General Population; Hepatic steatosis; Left ventricular mass index; Study of Health in Pomerania

Conflict of interest statement

Conflict-of-interest statement: The authors declare that they have no conflicts of interest.

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