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J Radioanal Nucl Chem. 2017;313(2):279-289. doi: 10.1007/s10967-017-5323-x. Epub 2017 Jun 13.

Somatostatin analogues labeled with copper radioisotopes: current status.

Journal of radioanalytical and nuclear chemistry

Aleksandra Marciniak, Justyna Brasuń

Affiliations

  1. Department of Inorganic Chemistry, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.

PMID: 28804185 PMCID: PMC5533839 DOI: 10.1007/s10967-017-5323-x

Abstract

Peptide receptor radionuclide therapy (PRRT) is a promising way to treat patients with inoperable tumors or metastatic neuroendocrine tumors. This therapeutic strategy is using radiolabeled peptides, which are capable of selective biding to receptors overexpressed in the cancer cells. One of the group of receptor-avid peptide used in the PRRT are the analogues of somatostatin (SST) connected to the complexes of radionuclides (e.g.

Keywords: Copper radionuclides; Radiopharmaceuticals; Somatostatin; Somatostatin analogues

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