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Xing W, Liu X, He Q, et al. BRAF. Oncol Lett. 2017;14(3):2903-2911doi: 10.3892/ol.2017.6486.
Xing, W., Liu, X., He, Q., Zhang, Z., & Jiang, Z. (2017). BRAF. Oncology letters, 14(3), 2903-2911. https://doi.org/10.3892/ol.2017.6486
Xing, Wanjia, et al. "BRAF." Oncology letters vol. 14,3 (2017): 2903-2911. doi: https://doi.org/10.3892/ol.2017.6486
Xing W, Liu X, He Q, Zhang Z, Jiang Z. BRAF. Oncol Lett. 2017 Sep;14(3):2903-2911. doi: 10.3892/ol.2017.6486. Epub 2017 Jun 28. PMID: 28928829; PMCID: PMC5588167.
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Oncol Lett. 2017 Sep;14(3):2903-2911. doi: 10.3892/ol.2017.6486. Epub 2017 Jun 28.

BRAF.

Oncology letters

Wanjia Xing, Xiaohong Liu, Qingqing He, Zongjing Zhang, Zhaoshun Jiang

Affiliations

  1. Department of Endocrinology, General Hospital of Jinan Military Command, Jinan, Shandong 250031, P.R. China.
  2. Department of Pathology, General Hospital of Jinan Military Command, Jinan, Shandong 250031, P.R. China.
  3. Department of Thyroid and Breast Surgery, General Hospital of Jinan Military Command, Jinan, Shandong 250031, P.R. China.

PMID: 28928829 PMCID: PMC5588167 DOI: 10.3892/ol.2017.6486

Abstract

Resistance to thyroid hormone (RTH) is a rare autosomal hereditary disorder characterized by increased serum thyroid hormone (TH) levels with unsuppressed or increased thyrotropin concentration. It remains unknown whether the coexistence of RTH with papillary thyroid carcinoma (PTC) and Hashimoto thyroiditis (HT) is incidental or whether it possesses a genetic or pathophysiological association. In the present study, a case of RTH with PTC and HT in an 11-year-old Chinese patient was examined and the clinical presentation of RTH with PTC was discussed. In addition, the possible associations between RTH, PTC and HT were determined. HT was confirmed in the patient using an autoimmune assay and thyroid ultrasound. RTH was diagnosed on the basis of clinical manifestations, laboratory information and gene analysis, and PTC was diagnosed according to histological results. Results of BRAF

Keywords: Hashimoto thyroiditis; bromocriptine; papillary thyroid carcinoma; resistance to thyroid hormone

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