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Front Immunol. 2017 Aug 21;8:985. doi: 10.3389/fimmu.2017.00985. eCollection 2017.

Reactivation of Intestinal Inflammation Is Suppressed by Catestatin in a Murine Model of Colitis .

Frontiers in immunology

Mohammad F Rabbi, Nour Eissa, Peris M Munyaka, Laƫtitia Kermarrec, Omar Elgazzar, Ehsan Khafipour, Charles N Bernstein, Jean Eric Ghia

Affiliations

  1. Department of Immunology, University of Manitoba, Winnipeg, MB, Canada.
  2. The Children Research Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB, Canada.
  3. Department of Animal Sciences, University of Manitoba, Winnipeg, MB, Canada.
  4. Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada.
  5. Department of Internal Medicine, Section of Gastroenterology, University of Manitoba, Winnipeg, MB, Canada.
  6. Inflammatory Bowel Disease Clinical and Research Centre, University of Manitoba, Winnipeg, MB, Canada.

PMID: 28871257 PMCID: PMC5566981 DOI: 10.3389/fimmu.2017.00985

Abstract

While there is growing awareness of a relationship between chromogranin-A (CHGA) and susceptibility to inflammatory conditions, the role of human catestatin [(hCTS); CHGA

Keywords: M1 and M2 macrophage; catestatin; chromogranin-A; gut dysbiosis; gut inflammation; inflammatory bowel disease

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