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Parikh GR, Peter E, Kakouros N. Complex Coronary Hemodynamics - Simple Analog Modelling as an Educational Tool. Open Med Inform J. 2017;11:12-19doi: 10.2174/1874431101711010012.
Parikh, G. R., Peter, E., & Kakouros, N. (2017). Complex Coronary Hemodynamics - Simple Analog Modelling as an Educational Tool. The open medical informatics journal, 1112-19. https://doi.org/10.2174/1874431101711010012
Parikh, Gaurav R, et al. "Complex Coronary Hemodynamics - Simple Analog Modelling as an Educational Tool." The open medical informatics journal vol. 11 (2017): 12-19. doi: https://doi.org/10.2174/1874431101711010012
Parikh GR, Peter E, Kakouros N. Complex Coronary Hemodynamics - Simple Analog Modelling as an Educational Tool. Open Med Inform J. 2017 Jul 28;11:12-19. doi: 10.2174/1874431101711010012. eCollection 2017. PMID: 28932342; PMCID: PMC5585460.
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Open Med Inform J. 2017 Jul 28;11:12-19. doi: 10.2174/1874431101711010012. eCollection 2017.

Complex Coronary Hemodynamics - Simple Analog Modelling as an Educational Tool.

The open medical informatics journal

Gaurav R Parikh, Elvis Peter, Nikolaos Kakouros

Affiliations

  1. Division of Cardiovascular Medicine, University of Massachusetts, 55 Lake Ave North, Worcester, MA, 01655. USA.
  2. Department of Cardiology, Marshfield Clinic, Weston Center 3501 Cranberry Blvd, Weston, WI 54476, USA.

PMID: 28932342 PMCID: PMC5585460 DOI: 10.2174/1874431101711010012

Abstract

OBJECTIVE: Invasive coronary angiography remains the cornerstone for evaluation of coronary stenoses despite there being a poor correlation between luminal loss assessment by coronary luminography and myocardial ischemia. This is especially true for coronary lesions deemed moderate by visual assessment. Coronary pressure-derived fractional flow reserve (FFR) has emerged as the gold standard for the evaluation of hemodynamic significance of coronary artery stenosis, which is cost effective and leads to improved patient outcomes. There are, however, several limitations to the use of FFR including the evaluation of serial stenoses.

METHOD: In this article, we discuss the electronic-hydraulic analogy and the utility of simple electrical modelling to mimic the coronary circulation and coronary stenoses. We exemplify the effect of tandem coronary lesions on the FFR by modelling of a patient with sequential disease segments and complex anatomy.

RESULTS: We believe that such computational modelling can serve as a powerful educational tool to help clinicians better understand the complexity of coronary hemodynamics and improve patient care.

Keywords: Computational modelling; Coronary angiography; Coronary hemodynamics; Educational tools; Myocardial fractional flow reserve; System equivalence

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