Toxicol Rep. 2014 Jun 11;1:300-308. doi: 10.1016/j.toxrep.2014.06.002. eCollection 2014.
Assessment of genotoxicity of some common food preservatives using .
Toxicology reports
Himadri Pandey, Vikas Kumar, B K Roy
Affiliations
Affiliations
- Laboratory of Cytogenetics, Department of Botany, Banaras Hindu University, Varanasi 221005, India.
PMID: 28962247
PMCID: PMC5598233 DOI: 10.1016/j.toxrep.2014.06.002
Abstract
Food preservatives play important role in today's food supplies that are used to prolong the self-life of products by protecting them from deterioration caused by micro-organisms. In this study, investigations were carried out to study the impacts of food preservatives like butylated hydroxytoluene, butylated hydroxyanisole, sorbic acid, propyl gallate and sodium nitrate. The effects of these preservatives at concentration of 1000 ppm, 1500 ppm, 2000 ppm, 2500 ppm for 4 h, 8 h and 16 h of exposure period were studied on the root tips of
Keywords: Allium cepa; B, bridge; BHA, butylated hydroxyanisol; BHT, butylated hydroxyltoluene; BN, binucleated; Butylated hydroxyanisol (PubChem CID: 517036); Butylated hydroxyltoluene (PubChem CID: 31404); CA, chromosome aberration; CB, chromosomal break; Chromosomal abnormalities; Food preservatives; Genotoxicity; MI, mitotic index; MP, multipolarity; Mitotic index; PG, propyl gallate; Propyl gallate (PubChem CID: 4947); SA, sorbic acid; SN, sodium nitrate; Sodium nitrate (PubChem CID: 24268); Sorbic acid (PubChem CID: 643460)
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