Display options
Cite
Staszewski J, Piusińska-Macoch R, Brodacki B, et al. Vascular parkinsonism and vascular dementia are associated with an increased risk of vascular events or death. Arch Med Sci Atheroscler Dis. 2017;2(1):e16-e23doi: 10.5114/amsad.2017.68549.
Staszewski, J., Piusińska-Macoch, R., Brodacki, B., Skrobowska, E., Macek, K., & Stępień, A. (2017). Vascular parkinsonism and vascular dementia are associated with an increased risk of vascular events or death. Archives of medical sciences. Atherosclerotic diseases, 2(1), e16-e23. https://doi.org/10.5114/amsad.2017.68549
Staszewski, Jacek, et al. "Vascular parkinsonism and vascular dementia are associated with an increased risk of vascular events or death." Archives of medical sciences. Atherosclerotic diseases vol. 2,1 (2017): e16-e23. doi: https://doi.org/10.5114/amsad.2017.68549
Staszewski J, Piusińska-Macoch R, Brodacki B, Skrobowska E, Macek K, Stępień A. Vascular parkinsonism and vascular dementia are associated with an increased risk of vascular events or death. Arch Med Sci Atheroscler Dis. 2017 Jun 23;2(1):e16-e23. doi: 10.5114/amsad.2017.68549. eCollection 2017. PMID: 28905043; PMCID: PMC5596114.
Copy Download .nbib Format: NLM
Share it on

Arch Med Sci Atheroscler Dis. 2017 Jun 23;2(1):e16-e23. doi: 10.5114/amsad.2017.68549. eCollection 2017.

Vascular parkinsonism and vascular dementia are associated with an increased risk of vascular events or death.

Archives of medical sciences. Atherosclerotic diseases

Jacek Staszewski, Renata Piusińska-Macoch, Bogdan Brodacki, Ewa Skrobowska, Katarzyna Macek, Adam Stępień

Affiliations

  1. Clinic of Neurology, Military Institute of Medicine, Warsaw, Poland.
  2. Department of Radiology, Military Institute of Medicine, Warsaw, Poland.

PMID: 28905043 PMCID: PMC5596114 DOI: 10.5114/amsad.2017.68549

Abstract

INTRODUCTION: The natural course of vascular parkinsonism (VaP) and dementia (VaD) due to cerebral small vessel disease (SVD) is not well known. The aim of this single-center study was to evaluate the long-term risk of vascular events, death and dependency in patients with VaP or VaD and to compare it with patients without cerebrovascular disease but with high atherothrombotic risk.

MATERIAL AND METHODS: Seventy-eight consecutive, functionally independent patients with MRI features of SVD and with recently diagnosed VaD (

RESULTS: Patients with SVD had lower prevalence of coronary artery disease compared with the CG (20.5% vs. 40%;

CONCLUSIONS: Patients with VaP or VaD due to SVD had significantly higher risk of vascular events, death and dependency compared to controls with high cardiovascular risk and without cerebrovascular disease.

Keywords: cerebral small vessel disease; mortality; prognosis; vascular dementia; vascular events; vascular parkinsonism

Conflict of interest statement

The authors declare no conflict of interest.

References

  1. Neuroepidemiology. 2005;25(2):75-84 - PubMed
  2. Parkinsonism Relat Disord. 2016 Nov;32:36-41 - PubMed
  3. Cerebrovasc Dis. 2001;12(3):171-80 - PubMed
  4. Lancet Neurol. 2010 Jul;9(7):689-701 - PubMed
  5. AJR Am J Roentgenol. 1987 Aug;149(2):351-6 - PubMed
  6. Eur Heart J. 2011 Jul;32(14):1769-818 - PubMed
  7. Am Fam Physician. 2010 Feb 15;81(4):470-6 - PubMed
  8. Stroke. 2001 Dec 1;32(12):2735-40 - PubMed
  9. Arch Neurol. 1993 Jun;50(6):643-50 - PubMed
  10. J Neurol Neurosurg Psychiatry. 2002 May;72(5):576-82 - PubMed
  11. BMC Neurol. 2011 Feb 28;11:29 - PubMed
  12. Stroke. 2013 Apr;44(4):995-1001 - PubMed
  13. Arch Neurol. 2000 Apr;57(4):507-12 - PubMed
  14. J Alzheimers Dis. 2016 May 6;53(1):117-25 - PubMed
  15. Brain. 2005 Nov;128(Pt 11):2507-17 - PubMed
  16. Arch Intern Med. 2007 Jan 8;167(1):81-8 - PubMed
  17. BMJ. 2010 Jul 26;341:c3666 - PubMed
  18. Neurology. 2014 Apr 15;82(15):1331-8 - PubMed
  19. Lancet. 2013 Aug 10;382(9891):507-15 - PubMed
  20. Neurosci J. 2013;2013:424695 - PubMed
  21. Ann Neurol. 2008 Feb;63(2):236-46 - PubMed
  22. Mov Disord. 2004 Jun;19(6):630-40 - PubMed
  23. JAMA. 2012 Jan 11;307(2):165-72 - PubMed
  24. J Stroke. 2015 May;17(2):101-10 - PubMed
  25. Neurology. 2009 Apr 21;72(16):1403-10 - PubMed
  26. Eur J Neurol. 2009 Apr;16(4):488-92 - PubMed
  27. Lancet Neurol. 2003 Apr;2(4):238-45 - PubMed
  28. Neurology. 1992 Mar;42(3 Pt 1):473-80 - PubMed

Publication Types