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Ocón B, Pan J, Dinh TT, et al. A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15. Front Immunol. 2017;8:1111doi: 10.3389/fimmu.2017.01111.
Ocón, B., Pan, J., Dinh, T. T., Chen, W., Ballet, R., Bscheider, M., Habtezion, A., Tu, H., Zabel, B. A., & Butcher, E. C. (2017). A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15. Frontiers in immunology, 81111. https://doi.org/10.3389/fimmu.2017.01111
Ocón, Borja, et al. "A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15." Frontiers in immunology vol. 8 (2017): 1111. doi: https://doi.org/10.3389/fimmu.2017.01111
Ocón B, Pan J, Dinh TT, Chen W, Ballet R, Bscheider M, Habtezion A, Tu H, Zabel BA, Butcher EC. A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15. Front Immunol. 2017 Sep 07;8:1111. doi: 10.3389/fimmu.2017.01111. eCollection 2017. PMID: 28936214; PMCID: PMC5594226.
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Front Immunol. 2017 Sep 07;8:1111. doi: 10.3389/fimmu.2017.01111. eCollection 2017.

A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15.

Frontiers in immunology

Borja Ocón, Junliang Pan, Theresa Thu Dinh, Wenjing Chen, Romain Ballet, Michael Bscheider, Aida Habtezion, Hua Tu, Brian A Zabel, Eugene C Butcher

Affiliations

  1. The Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System and The Palo Alto Veterans Institute for Research, Palo Alto, CA, United States.
  2. Laboratory of Immunology and Vascular Biology, Department of Pathology, School of Medicine, Stanford University, Stanford, CA, United States.
  3. Lake Pharma, Inc., Belmont, CA, United States.
  4. Division of Gastroenterology and Hepatology, School of Medicine, Stanford University, Stanford, CA, United States.

PMID: 28936214 PMCID: PMC5594226 DOI: 10.3389/fimmu.2017.01111

Abstract

Chemoattractants control lymphocyte recruitment from the blood, contributing to the systemic organization of the immune system. The G protein-linked receptor GPR15 mediates lymphocyte homing to the large intestines and skin. Here we show that the 9 kDa CC-motif containing cationic polypeptide AP57/colon-derived sushi containing domain-2 binding factor (CSBF), encoded by

Keywords: GPR15; T cells; chemokine; colon; ligand; skin; trafficking receptor

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