Display options
Share it on

Curr Treatm Opt Rheumatol. 2016;2(4):312-320. doi: 10.1007/s40674-016-0056-5. Epub 2016 Oct 13.

Management of Widespread Pain and Fibromyalgia.

Current treatment options in rheumatology

Daniel Whibley, Linda E Dean, Neil Basu

Affiliations

  1. Epidemiology Group, Institute of Applied Health Sciences, University of Aberdeen, School of Medicine and Dentistry, Foresterhill, Aberdeen, Scotland AB25 2ZD UK.

PMID: 28936388 PMCID: PMC5566487 DOI: 10.1007/s40674-016-0056-5

Abstract

Specialists' views of fibromyalgia (FM) are typically colored by their experiences of the selected, complex cases that they are regularly called to evaluate. At a population level, it is crucial to recognize that education which promotes patient empowerment and non-pharmacological interventions which support self-management are very effective. The temptation, for both physician and patient, to first reach for pharmacological interventions should be resisted until such holistic approaches are explored. In particular, a strong evidence base supports graded exercise and cognitive behavioral therapies, but such treatments must be intelligently "prescribed." As reflected by the recent ACR criteria, FM is a highly heterogeneous disorder and is not simply a disorder of pain. For some patients, co-occurring symptoms, such as fatigue, can be equally as impactful and so management strategies should be sufficiently versatile to target those dimensions which are considered priorities at the level of the individual patient. In those patients who do require pharmacological support, patients should not be led to expect significant gains in isolation. The importance of self-management requires emphasis at each and every tier of management. It is true that advances in our understanding of neurobiology have greatly informed the selection of adjunctive drug classes which may provide benefit (as well as those which do not-as is the case of opioids). However, further unpicking of pathogenesis is still required if the FM landscape is to move further towards drug-led management.

Keywords: Chronic widespread pain; Fibromyalgia

References

  1. Cochrane Database Syst Rev. 2007 Oct 17;(4):CD003786 - PubMed
  2. Curr Pain Headache Rep. 2013 Aug;17(8):356 - PubMed
  3. J Orthop Sports Phys Ther. 2016 Feb;46(2):38-43 - PubMed
  4. J Rheumatol. 2011 Jun;38(6):1113-22 - PubMed
  5. Br Med J. 1904 Jan 16;1(2246):117-21 - PubMed
  6. RMD Open. 2015 Feb 18;1(1):e000026 - PubMed
  7. Schmerz. 2012 Jun;26(3):247-58 - PubMed
  8. Disabil Rehabil. 2013 Jan;35(1):1-10 - PubMed
  9. Arthritis Rheum. 1995 Jan;38(1):19-28 - PubMed
  10. BMC Psychiatry. 2016 Jan 15;16:4 - PubMed
  11. Arthritis Rheum. 2007 Apr;56(4):1336-44 - PubMed
  12. Rheumatology (Oxford). 2011 Mar;50(3):532-43 - PubMed
  13. Am J Nurs. 2016 Jan;116(1):24-32; quiz 33, 41 - PubMed
  14. Cochrane Database Syst Rev. 2014 Jan 03;(1):CD007115 - PubMed
  15. Arthritis Res Ther. 2009;11(4):R120 - PubMed
  16. J Clin Pharmacol. 2012 Jan;52(1):6-17 - PubMed
  17. Cochrane Database Syst Rev. 2013 Sep 10;(9):CD009796 - PubMed
  18. Scand J Rheumatol Suppl. 2000;113:32-6 - PubMed
  19. Cochrane Database Syst Rev. 2013 Oct 16;(10):CD010782 - PubMed
  20. Cochrane Database Syst Rev. 2013 Jan 31;(1):CD010292 - PubMed
  21. JAMA. 2014 Apr 16;311(15):1547-55 - PubMed
  22. Pain Pract. 2011 Nov-Dec;11(6):516-27 - PubMed
  23. Eur J Pain. 2014 Sep;18(8):1067-80 - PubMed
  24. Arthritis Rheum. 1990 Feb;33(2):160-72 - PubMed
  25. Pain Res Manag. 2013 May-Jun;18(3):119-26 - PubMed
  26. Rheumatology (Oxford). 2008 Dec;47(12):1741-6 - PubMed
  27. Curr Pain Headache Rep. 2004 Oct;8(5):369-78 - PubMed
  28. Arthritis Care Res (Hoboken). 2010 May;62(5):600-10 - PubMed
  29. Arthritis Care Res (Hoboken). 2013 May;65(5):786-92 - PubMed
  30. Cochrane Database Syst Rev. 2013 Dec 20;(12):CD010884 - PubMed
  31. Expert Opin Pharmacother. 2015 Jun;16(9):1347-68 - PubMed
  32. Cochrane Database Syst Rev. 2014 Oct 28;(10):CD011336 - PubMed
  33. J Pain. 2014 May;15(5):507-15 - PubMed

Publication Types