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Plants (Basel). 2017 Sep 22;6(4). doi: 10.3390/plants6040042.

Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts.

Plants (Basel, Switzerland)

Ammar Altemimi, Naoufal Lakhssassi, Azam Baharlouei, Dennis G Watson, David A Lightfoot

Affiliations

  1. Department of Food Science, College of Agriculture, University of Al-Basrah, Basrah 61004, Iraq. [email protected].
  2. Department of Plant, Soil and Agricultural Systems, Plant Biotechnology and Genome Core-Facility, Southern Illinois University at Carbondale, Carbondale, IL 62901, USA. [email protected].
  3. Department of Plant, Soil and Agricultural Systems, Plant Biotechnology and Genome Core-Facility, Southern Illinois University at Carbondale, Carbondale, IL 62901, USA. [email protected].
  4. Department of Plant, Soil and Agricultural Systems, Plant Biotechnology and Genome Core-Facility, Southern Illinois University at Carbondale, Carbondale, IL 62901, USA. [email protected].
  5. Department of Plant, Soil and Agricultural Systems, Plant Biotechnology and Genome Core-Facility, Southern Illinois University at Carbondale, Carbondale, IL 62901, USA. [email protected].

PMID: 28937585 PMCID: PMC5750618 DOI: 10.3390/plants6040042

Abstract

There are concerns about using synthetic phenolic antioxidants such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) as food additives because of the reported negative effects on human health. Thus, a replacement of these synthetics by antioxidant extractions from various foods has been proposed. More than 8000 different phenolic compounds have been characterized; fruits and vegetables are the prime sources of natural antioxidants. In order to extract, measure, and identify bioactive compounds from a wide variety of fruits and vegetables, researchers use multiple techniques and methods. This review includes a brief description of a wide range of different assays. The antioxidant, antimicrobial, and anticancer properties of phenolic natural products from fruits and vegetables are also discussed.

Keywords: BHT; antimicrobial; antioxidants; medicinal plants

Conflict of interest statement

The authors declare no conflicts of interest.

References

  1. Food Chem. 2008 Jul 1;109(1):54-63 - PubMed
  2. Crit Rev Food Sci Nutr. 1996 Feb;36(3):175-224 - PubMed
  3. J Natl Cancer Inst. 1999 Feb 3;91(3):215-25 - PubMed
  4. Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):7915-22 - PubMed
  5. J Agric Food Chem. 2005 Jun 15;53(12):4667-79 - PubMed
  6. BMC Plant Biol. 2012 Feb 27;12:30 - PubMed
  7. Am J Clin Nutr. 1997 Apr;65(4):1088-90 - PubMed
  8. Indian J Exp Biol. 2007 May;45(5):480-5 - PubMed
  9. Eur J Pharmacol. 2008 May 13;585(2-3):325-37 - PubMed
  10. J Inflamm (Lond). 2010 Sep 14;7:47 - PubMed
  11. Nat Prod Res. 2010 Feb;24(3):300-4 - PubMed
  12. N Engl J Med. 1990 Aug 16;323(7):439-45 - PubMed
  13. Planta Med. 2000 Dec;66(8):687-93 - PubMed
  14. Front Plant Sci. 2017 Mar 13;8:324 - PubMed
  15. FEBS J. 2008 Aug;275(15):3804-14 - PubMed
  16. Naturwissenschaften. 2009 Jan;96(1):129-33 - PubMed
  17. PLoS One. 2007 Jan 31;2(1):e178 - PubMed
  18. J Biomed Biotechnol. 2004;2004(5):239-240 - PubMed
  19. Molecules. 2010 Dec 03;15(12):8813-26 - PubMed
  20. Toxicol Lett. 2004 Apr 15;150(1):57-83 - PubMed
  21. J Pharm Biomed Anal. 2004 Feb 4;34(2):349-57 - PubMed
  22. Afr J Tradit Complement Altern Med. 2007 Feb 16;4(3):313-8 - PubMed
  23. Talanta. 2008 Jun 15;75(5):1332-7 - PubMed
  24. Indian J Pharmacol. 2009 Oct;41(5):233-6 - PubMed
  25. Nutr Cancer. 1992;18(1):1-29 - PubMed
  26. Evid Based Complement Alternat Med. 2013;2013:801501 - PubMed
  27. Int J Biochem Cell Biol. 1997 Nov;29(11):1297-301 - PubMed
  28. Antioxidants (Basel). 2017 May 17;6(2): - PubMed
  29. Cancer Res. 1996 Mar 15;56(6):1291-5 - PubMed
  30. Arch Microbiol. 2017 Dec;199(10 ):1417-1429 - PubMed
  31. Fitoterapia. 2007 Sep;78(6):423-5 - PubMed
  32. Nat Prod Res. 2010 Jul;24(12):1168-76 - PubMed
  33. Chem Cent J. 2015 Jun 20;9:39 - PubMed
  34. Molecules. 2008;13(10):2545-56 - PubMed
  35. J Agric Food Chem. 1999 Jun;47(6):2207-12 - PubMed
  36. Life Sci. 2004 Mar 12;74(17):2157-84 - PubMed
  37. Chem Biol Interact. 2006 Mar 10;160(1):1-40 - PubMed
  38. J Chromatogr A. 2006 Jan 13;1102(1-2):193-9 - PubMed
  39. Ultrason Sonochem. 2004 May;11(3-4):261-5 - PubMed
  40. Plant Physiol. 2009 Nov;151(3):1030-40 - PubMed
  41. Am J Clin Nutr. 1997 May;65(5 Suppl):1628S-1644S - PubMed
  42. J Chromatogr A. 2009 Jan 9;1216(2):217-29 - PubMed
  43. Plant Physiol Biochem. 2009 Jan;47(1):37-41 - PubMed
  44. Plant Physiol. 2017 Jul;174(3):1531-1543 - PubMed
  45. J Agric Food Chem. 2002 Jan 2;50(1):81-6 - PubMed
  46. Life Sci. 2003 Aug 15;73(13):1667-81 - PubMed
  47. Asia Pac J Clin Nutr. 2007;16 Suppl 1:158-63 - PubMed
  48. J Clin Microbiol. 2010 Apr;48(4):1169-75 - PubMed
  49. Lancet. 2003 Jun 14;361(9374):2017-23 - PubMed
  50. J Food Sci. 2008 Mar;73(2):M37-46 - PubMed
  51. Nat Prod Res. 2007 Aug;21(10 ):857-66 - PubMed
  52. J Pharm Biomed Anal. 2006 Aug 28;41(5):1523-42 - PubMed
  53. Ultrason Sonochem. 2011 Nov;18(6):1279-86 - PubMed
  54. Crit Rev Food Sci Nutr. 1995 Jan;35(1-2):7-20 - PubMed
  55. Molecules. 2015 Apr 14;20(4):6611-25 - PubMed
  56. J Agric Food Chem. 2003 Oct 22;51(22):6475-81 - PubMed
  57. J Agric Food Chem. 2002 Aug 14;50(17):4976-82 - PubMed
  58. Fitoterapia. 2006 Jun;77(4):290-5 - PubMed
  59. Braz J Med Biol Res. 2004 Mar;37(3):379-84 - PubMed

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