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Svejstrup TD, Ruffoni A, Juliá F, et al. Synthesis of Arylamines via Aminium Radicals. Angew Chem Int Ed Engl. 2017;56(47):14948-14952doi: 10.1002/anie.201708693.
Svejstrup, T. D., Ruffoni, A., Juliá, F., Aubert, V. M., & Leonori, D. (2017). Synthesis of Arylamines via Aminium Radicals. Angewandte Chemie (International ed. in English), 56(47), 14948-14952. https://doi.org/10.1002/anie.201708693
Svejstrup, Thomas D, et al. "Synthesis of Arylamines via Aminium Radicals." Angewandte Chemie (International ed. in English) vol. 56,47 (2017): 14948-14952. doi: https://doi.org/10.1002/anie.201708693
Svejstrup TD, Ruffoni A, Juliá F, Aubert VM, Leonori D. Synthesis of Arylamines via Aminium Radicals. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14948-14952. doi: 10.1002/anie.201708693. Epub 2017 Oct 24. PMID: 28967171; PMCID: PMC5698739.
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Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14948-14952. doi: 10.1002/anie.201708693. Epub 2017 Oct 24.

Synthesis of Arylamines via Aminium Radicals.

Angewandte Chemie (International ed. in English)

Thomas D Svejstrup, Alessandro Ruffoni, Fabio Juliá, Valentin M Aubert, Daniele Leonori

Affiliations

  1. School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.

PMID: 28967171 PMCID: PMC5698739 DOI: 10.1002/anie.201708693

Abstract

Arylamines constitute the core structure of many therapeutic agents, agrochemicals, and organic materials. The development of methods for the efficient and selective construction of these structural motifs from simple building blocks is desirable but still challenging. We demonstrate that protonated electron-poor O-aryl hydroxylamines give aminium radicals in the presence of Ru(bpy)

© 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Keywords: N-arylation; aminium radicals; aryl amines; late-stage amination; synthetic methods

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