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Seki N, Yamazaki N, Ikeda T, et al. A Symptomatic Case of Adenomatous Ductal Proliferation/Hyperplasia with a Large Cystic Lesion. Case Rep Oncol. 2017;10(2):676-682doi: 10.1159/000478997.
Seki, N., Yamazaki, N., Ikeda, T., Hadara, H., & Himi, T. (2017). A Symptomatic Case of Adenomatous Ductal Proliferation/Hyperplasia with a Large Cystic Lesion. Case reports in oncology, 10(2), 676-682. https://doi.org/10.1159/000478997
Seki, Nobuhiko, et al. "A Symptomatic Case of Adenomatous Ductal Proliferation/Hyperplasia with a Large Cystic Lesion." Case reports in oncology vol. 10,2 (2017): 676-682. doi: https://doi.org/10.1159/000478997
Seki N, Yamazaki N, Ikeda T, Hadara H, Himi T. A Symptomatic Case of Adenomatous Ductal Proliferation/Hyperplasia with a Large Cystic Lesion. Case Rep Oncol. 2017 Jul 27;10(2):676-682. doi: 10.1159/000478997. eCollection 2017. PMID: 28878649; PMCID: PMC5582527.
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Case Rep Oncol. 2017 Jul 27;10(2):676-682. doi: 10.1159/000478997. eCollection 2017.

A Symptomatic Case of Adenomatous Ductal Proliferation/Hyperplasia with a Large Cystic Lesion.

Case reports in oncology

Nobuhiko Seki, Norikazu Yamazaki, Tatsuru Ikeda, Hiroshi Hadara, Tetsuo Himi

Affiliations

  1. Teine Clover Otolaryngology Clinic, Sapporo, Japan.
  2. Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo, Japan.
  3. Department of Otolaryngology, Hakodate Goryokaku Hospital, Hakodate, Japan.
  4. Pathology Center, Hakodate Goryokaku Hospital, Hakodate, Japan.
  5. Department of Diagnostic Pathology, Seichokai Fuchu Hospital, Izumi, Japan.

PMID: 28878649 PMCID: PMC5582527 DOI: 10.1159/000478997

Abstract

Adenomatous ductal proliferation/hyperplasia (ADP/H) of the salivary gland, a rare asymptomatic nonneoplastic lesion that histopathologically resembles basal cell adenoma, is typically incidentally identified in resected specimens of other salivary diseases such as tumors and chronic sialadenitis. A 70-year-old male was referred to our hospital with a 9-month history of continuous swelling in the left parotid region. A physical examination revealed a soft mass in the left parotid gland, which was identified as a cystic mass by computed tomography. A parotid tumor with cystic components was suspected, and partial parotidectomy was performed under general anesthesia. The histopathological findings were consistent with the diagnosis of ADP/H of the salivary gland. This case report emphasizes the necessity for a proper diagnosis of ADP/H of the salivary gland. Further large case series are required for a modification of the definition of ADP/H for its correct diagnosis.

Keywords: Adenomatous ductal proliferation/hyperplasia; Neoplasm; Salivary gland disease

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