Front Microbiol. 2017 Aug 23;8:1581. doi: 10.3389/fmicb.2017.01581. eCollection 2017.
Frontiers in microbiology
Thippeswamy H Sannasiddappa, Peter A Lund, Simon R Clarke
PMID: 28878747 PMCID: PMC5572772 DOI: 10.3389/fmicb.2017.01581
Bile salts are potent antimicrobial agents and are an important component of innate defenses in the intestine, giving protection against invasive organisms. They play an important role in determining microbial ecology of the intestine and alterations in their levels can lead to increased colonization by pathogens. We have previously demonstrated survival of the opportunistic pathogen
Keywords: antibacterial; bile salts; intracellular pH; membrane permeability; viability