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Fadıloğlu E, Karalök A, Türkmen O, et al. Amphricrine carcinoma of the cervix-adeno neuroendocrine tumor: A case report. Turk J Obstet Gynecol. 2016;13(2):99-102doi: 10.4274/tjod.72325.
Fadıloğlu, E., Karalök, A., Türkmen, O., Asiltürk, �. �., Öçalan, R., Boran, N., Ökten, H., Turan, T., & Tulunay, G. (2016). Amphricrine carcinoma of the cervix-adeno neuroendocrine tumor: A case report. Turkish journal of obstetrics and gynecology, 13(2), 99-102. https://doi.org/10.4274/tjod.72325
Fadıloğlu, Erdem, et al. "Amphricrine carcinoma of the cervix-adeno neuroendocrine tumor: A case report." Turkish journal of obstetrics and gynecology vol. 13,2 (2016): 99-102. doi: https://doi.org/10.4274/tjod.72325
Fadıloğlu E, Karalök A, Türkmen O, Asiltürk Ş, Öçalan R, Boran N, Ökten H, Turan T, Tulunay G. Amphricrine carcinoma of the cervix-adeno neuroendocrine tumor: A case report. Turk J Obstet Gynecol. 2016 Jun;13(2):99-102. doi: 10.4274/tjod.72325. Epub 2016 Jun 15. PMID: 28913101; PMCID: PMC5558347.
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Turk J Obstet Gynecol. 2016 Jun;13(2):99-102. doi: 10.4274/tjod.72325. Epub 2016 Jun 15.

Amphricrine carcinoma of the cervix-adeno neuroendocrine tumor: A case report.

Turkish journal of obstetrics and gynecology

Erdem Fadıloğlu, Alper Karalök, Osman Türkmen, Şeyma Asiltürk, Reyhan Öçalan, Nurettin Boran, Heyecan Ökten, Taner Turan, Gökhan Tulunay

Affiliations

  1. Etlik Zübeyde Han?m Women's Health Training and Research Hospital, Clinic of Gynecologic Oncology, Ankara, Turkey.
  2. Etlik Zübeyde Han?m Women's Health Training and Research Hospital, Clinic of Pathology, Ankara, Turkey.

PMID: 28913101 PMCID: PMC5558347 DOI: 10.4274/tjod.72325

Abstract

Adenoneuroendocrine carcinoma is a very rare form of cervical carcinoma that includes both endocrine and exocrine components. In general terms, these carcinomas progress aggressively and show early metastases due to the neuroendocrine component. The most important criteria related to prognosis is the stage of the disease. Without clearly determined therapeutic protocols this carcinoma is generally seen at earlier ages and causes high mortality. Many radiotherapy and multidrug chemotherapy protocols are used after surgical intervention. Detection of the neuroendocrine component of cervical tumors is achieved through immunohistochemical staining. Herein, we present a woman aged 50 years who was admitted to the hospital with abdominal pain and postmenopausal vaginal bleeding whose examination revealed a cervical tumor. A pathologic examination after surgery resulted as "adenocarcinoma and large cell neuroendocrine carcinoma." Afterwards, a combined chemotherapy regimen (cisplatin + etoposid) was administered to the patient and 6 months of progress is evaluated in this report.

Keywords: Cervical carcinoma; amphicrine tumor; neuroendochrine tumor

Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

References

  1. Tohoku J Exp Med. 2013;229(1):75-81 - PubMed
  2. Obstet Gynecol Sci. 2013 Nov;56(6):420-5 - PubMed
  3. Pathologe. 2005 Jul;26(4):262-5 - PubMed
  4. J Med Assoc Thai. 2015 Aug;98(8):725-33 - PubMed
  5. Arch Gynecol Obstet. 2012 Nov;286(5):1247-53 - PubMed
  6. Zhonghua Fu Chan Ke Za Zhi. 2015 Mar;50(3):198-203 - PubMed
  7. Am J Surg Pathol. 1987;11 Suppl 1:71-86 - PubMed
  8. Gynecol Oncol. 2001 Jul;82(1):187-91 - PubMed
  9. Int J Gynecol Pathol. 2012 Sep;31(5):490-6 - PubMed
  10. Cancer. 1998 Oct 1;83(7):1391-400 - PubMed
  11. J Chemother. 2006 Apr;18(2):209-16 - PubMed

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