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Rwegerera GM, Rivera YP, Zhou F, et al. Disseminated Burkitt's Lymphoma with a Pancreatic Mass in a HIV Positive Woman Diagnosed by Axillary Lymph Node Biopsy. J Clin Diagn Res. 2017;11(8):OD14-OD16doi: 10.7860/JCDR/2017/27456.10493.
Rwegerera, G. M., Rivera, Y. P., Zhou, F., Chobanga, K. J., & Sesay, S. O. (2017). Disseminated Burkitt's Lymphoma with a Pancreatic Mass in a HIV Positive Woman Diagnosed by Axillary Lymph Node Biopsy. Journal of clinical and diagnostic research : JCDR, 11(8), OD14-OD16. https://doi.org/10.7860/JCDR/2017/27456.10493
Rwegerera, Godfrey Mutashambara, et al. "Disseminated Burkitt's Lymphoma with a Pancreatic Mass in a HIV Positive Woman Diagnosed by Axillary Lymph Node Biopsy." Journal of clinical and diagnostic research : JCDR vol. 11,8 (2017): OD14-OD16. doi: https://doi.org/10.7860/JCDR/2017/27456.10493
Rwegerera GM, Rivera YP, Zhou F, Chobanga KJ, Sesay SO. Disseminated Burkitt's Lymphoma with a Pancreatic Mass in a HIV Positive Woman Diagnosed by Axillary Lymph Node Biopsy. J Clin Diagn Res. 2017 Aug;11(8):OD14-OD16. doi: 10.7860/JCDR/2017/27456.10493. Epub 2017 Aug 01. PMID: 28969187; PMCID: PMC5620828.
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J Clin Diagn Res. 2017 Aug;11(8):OD14-OD16. doi: 10.7860/JCDR/2017/27456.10493. Epub 2017 Aug 01.

Disseminated Burkitt's Lymphoma with a Pancreatic Mass in a HIV Positive Woman Diagnosed by Axillary Lymph Node Biopsy.

Journal of clinical and diagnostic research : JCDR

Godfrey Mutashambara Rwegerera, Yordanka Pina Rivera, Feng Zhou, Kudra Jumanne Chobanga, Sheikh Omar Sesay

Affiliations

  1. Senior Lecturer, Department of Internal Medicine, Faculty of Medicine, University of Botswana and Princess Marina Hospital, Gaborone, Botswana.
  2. Lecturer, Department of Internal Medicine, Faculty of Medicine, University of Botswana and Princess Marina Hospital, Gaborone, Botswana.
  3. Pathologist, Department of Histopathology, National Health Laboratory Gaborone, Botswana.
  4. Lecturer, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Botswana and Princess Marina Hospital, Gaborone, Botswana.
  5. Consultant, Department of Radiology, Princess Marina Hospital, Gaborone, Botswana.

PMID: 28969187 PMCID: PMC5620828 DOI: 10.7860/JCDR/2017/27456.10493

Abstract

Burkitt's Lymphoma (BL) is a highly aggressive B cell lymphoma of non-Hodgkin's type usually presenting in extranodal sites for endemic and sporadic types of the disease. Like other non-Hodgkin's Lymphomas (NHL), HIV positive associated BL is associated with peripheral lymphadenopathy. We present a case of 22-year-old newly diagnosed HIV positive female patient who presented with generalized peripheral lymphadenopathy and obstructive jaundice. Initial work up was suggestive of acute pancreatitis with further evaluation revealing a pancreatic head mass. BL was confirmed both by axillary lymph node biopsy and immunohistochemistry, highlighting the importance of high index of suspicion and prompt histopathological diagnosis to enable treatment of this fatal disease that is potentially curable.

Keywords: Epstein-barr virus; Fatal outcome; Immunodeficiency; Young adult

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