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Lindström A, Midtbö K, Arnesson LG, et al. Fusion between M2-macrophages and cancer cells results in a subpopulation of radioresistant cells with enhanced DNA-repair capacity. Oncotarget. 2017;8(31):51370-51386doi: 10.18632/oncotarget.17986.
Lindström, A., Midtbö, K., Arnesson, L. G., Garvin, S., & Shabo, I. (2017). Fusion between M2-macrophages and cancer cells results in a subpopulation of radioresistant cells with enhanced DNA-repair capacity. Oncotarget, 8(31), 51370-51386. https://doi.org/10.18632/oncotarget.17986
Lindström, Annelie, et al. "Fusion between M2-macrophages and cancer cells results in a subpopulation of radioresistant cells with enhanced DNA-repair capacity." Oncotarget vol. 8,31 (2017): 51370-51386. doi: https://doi.org/10.18632/oncotarget.17986
Lindström A, Midtbö K, Arnesson LG, Garvin S, Shabo I. Fusion between M2-macrophages and cancer cells results in a subpopulation of radioresistant cells with enhanced DNA-repair capacity. Oncotarget. 2017 May 18;8(31):51370-51386. doi: 10.18632/oncotarget.17986. eCollection 2017 Aug 01. PMID: 28881654; PMCID: PMC5584255.
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Oncotarget. 2017 May 18;8(31):51370-51386. doi: 10.18632/oncotarget.17986. eCollection 2017 Aug 01.

Fusion between M2-macrophages and cancer cells results in a subpopulation of radioresistant cells with enhanced DNA-repair capacity.

Oncotarget

Annelie Lindström, Kristine Midtbö, Lars-Gunnar Arnesson, Stina Garvin, Ivan Shabo

Affiliations

  1. Division of Cell Biology, Department of Clinical and Experimental Medicine, Linköping University, SE 581 85, Linköping, Sweden.
  2. Division of Surgery, Department of Clinical and Experimental Medicine, Linköping University, SE 581 85, Linköping, Sweden.
  3. Department of Clinical Pathology, Department of Clinical and Experimental Medicine, Linköping University, SE 581 85, Linköping, Sweden.
  4. Endocrine and Sarcoma Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, SE 171 77, Stockholm, Sweden.
  5. Department of Breast and Endocrine Surgery, Karolinska University Hospital, SE 171 76, Stockholm, Sweden.

PMID: 28881654 PMCID: PMC5584255 DOI: 10.18632/oncotarget.17986

Abstract

Cell fusion is a natural biological process in normal development and tissue regeneration. Fusion between cancer cells and macrophages results in hybrids that acquire genetic and phenotypic characteristics from both maternal cells. There is a growing body of

Keywords: M2-macrophage; breast cancer; cell fusion; radioresistance; radiotherapy

Conflict of interest statement

CONFLICTS OF INTEREST The authors declare that they have no conflicts of interests.

References

  1. Science. 2013 Feb 1;339(6119):543-8 - PubMed
  2. Aging (Albany NY). 2014 May;6(5):353-4 - PubMed
  3. Int J Oral Maxillofac Surg. 2012 Aug;41(8):965-9 - PubMed
  4. N Engl J Med. 2002 Oct 17;347(16):1227-32 - PubMed
  5. Stem Cells. 2012 May;30(5):833-44 - PubMed
  6. Carcinogenesis. 2015 Jun;36(6):685-95 - PubMed
  7. Surgery. 2011 Dec;150(6):1032-9 - PubMed
  8. Hepatobiliary Surg Nutr. 2016 Apr;5(2):183-7 - PubMed
  9. Mol Cancer Ther. 2011 Sep;10(9):1698-708 - PubMed
  10. Nat Med. 2011 Jul 03;17(7):860-6 - PubMed
  11. PLoS One. 2012;7(8):e42653 - PubMed
  12. Int J Radiat Oncol Biol Phys. 1990 Jan;18(1):87-93 - PubMed
  13. Cloning Stem Cells. 2003;5(4):339-54 - PubMed
  14. Compend Contin Educ Vet. 2009 Sep;31(9):E1-14; quiz E14 - PubMed
  15. Nat Cell Biol. 2008 May;10(5):575-83 - PubMed
  16. Int J Radiat Oncol Biol Phys. 1994 Aug 30;30(1):11-6 - PubMed
  17. Curr Mol Pharmacol. 2012 Jan;5(1):36-53 - PubMed
  18. Radiat Res. 1998 Nov;150(5 Suppl):S42-51 - PubMed
  19. Bone Marrow Transplant. 2004 Jul;34(2):183-6 - PubMed
  20. Nature. 2014 Oct 2;514(7520):54-8 - PubMed
  21. Acta Oncol. 2008;47(5):809-24 - PubMed
  22. Radiat Oncol. 2017 Jan 13;12(1):16 - PubMed
  23. Antioxid Redox Signal. 2014 Jul 10;21(2):251-9 - PubMed
  24. PLoS One. 2009 Aug 06;4(8):e6530 - PubMed
  25. Science. 2013 Feb 1;339(6119):528-9 - PubMed
  26. Semin Radiat Oncol. 2012 Apr;22(2):100-7 - PubMed
  27. Science. 2005 Apr 15;308(5720):369-73 - PubMed
  28. Nature. 2013 Sep 19;501(7467):338-45 - PubMed
  29. PLoS One. 2013 Jun 26;8(6):e66731 - PubMed
  30. Annu Rev Pathol. 2013 Jan 24;8:277-302 - PubMed
  31. Int J Cancer. 2003 Aug 20;106(2):153-9 - PubMed
  32. Br J Cancer. 2011 Jan 18;104(2):361-8 - PubMed
  33. Clin Cancer Res. 2017 May 15;23(10):2414-2422 - PubMed
  34. Am J Pathol. 2012 Jun;180(6):2504-15 - PubMed
  35. Int J Cancer. 2009 Oct 15;125(8):1826-31 - PubMed
  36. Autophagy. 2013 Sep;9(9):1263-5 - PubMed
  37. Radiat Res. 1998 Apr;149(4):396-400 - PubMed
  38. Nat Rev Cancer. 2008 May;8(5):377-86 - PubMed
  39. Cancer Microenviron. 2014 Aug;7(1-2):61-9 - PubMed
  40. Int J Cancer. 2012 Nov 15;131(10):2320-31 - PubMed
  41. BMC Cancer. 2015 Nov 20;15:922 - PubMed
  42. Arch Toxicol. 2013 Jun;87(6):949-68 - PubMed
  43. Int J Mol Sci. 2016 Jan 14;17(1): - PubMed
  44. Int J Radiat Biol. 1990 Jun;57(6):1195-211 - PubMed
  45. Cancer. 2011 Sep 1;117(17):4092-9 - PubMed
  46. Bone Marrow Transplant. 2005 May;35(10):1021-4 - PubMed
  47. Mutagenesis. 2008 May;23(3):143-51 - PubMed
  48. Cancer Metastasis Rev. 2004 Aug-Dec;23(3-4):311-22 - PubMed
  49. Protein Expr Purif. 2011 Mar;76(1):136-44 - PubMed
  50. Biochemistry (Mosc). 2013 Nov;78(11):1201-15 - PubMed
  51. Contrib Microbiol. 2006;13:138-155 - PubMed
  52. Cancer Res. 1991 Sep 1;51(17):4671-6 - PubMed
  53. Cancer Cell Int. 2011 Jun 28;11(1):21 - PubMed
  54. Mutat Res. 2013 Oct;750(1-2):45-55 - PubMed
  55. Adv Exp Med Biol. 2007;608:1-22 - PubMed
  56. Int J Radiat Biol. 1999 Apr;75(4):395-405 - PubMed
  57. PLoS One. 2014 Feb 06;9(2):e87893 - PubMed
  58. Nature. 2009 Oct 22;461(7267):1071-8 - PubMed
  59. Proteomics. 2008 Nov;8(21):4521-33 - PubMed
  60. PLoS One. 2013;8(1):e55572 - PubMed
  61. Br J Cancer. 1996 Jul;74(1):1-5 - PubMed
  62. Nat Protoc. 2006;1(5):2315-9 - PubMed
  63. Med Hypotheses. 2009 Oct;73(4):542-7 - PubMed
  64. Lancet. 2005 Dec 17;366(9503):2087-106 - PubMed
  65. Semin Cancer Biol. 2015 Apr;31:36-42 - PubMed
  66. Oncogene. 2013 May 23;32(21):2649-60 - PubMed
  67. Cancer Res. 2011 Feb 15;71(4):1497-505 - PubMed
  68. Acta Diabetol. 2009 Mar;46(1):43-9 - PubMed
  69. Cell Biol Int. 1994 Mar;18(3):207-10 - PubMed
  70. Methods Mol Med. 2005;110:21-8 - PubMed
  71. Int J Cancer. 2008 Aug 15;123(4):780-6 - PubMed
  72. Mol Biotechnol. 2004 Mar;26(3):249-61 - PubMed
  73. Nature. 2009 Apr 9;458(7239):780-3 - PubMed
  74. Eur J Cancer. 2003 May;39(7):932-44 - PubMed
  75. Nat Rev Mol Cell Biol. 2004 Sep;5(9):752-62 - PubMed
  76. Nat Rev Cancer. 2007 Dec;7(12):968-76 - PubMed
  77. Exp Cell Res. 1994 Jun;212(2):176-89 - PubMed
  78. Cell Commun Signal. 2012 Apr 09;10(1):10 - PubMed
  79. Curr Drug Targets. 2016;17(4):460-6 - PubMed
  80. Adv Exp Med Biol. 2011;714:173-82 - PubMed
  81. Nat Cell Biol. 2008 May;10(5):584-92 - PubMed
  82. Eur J Cancer. 2013 Apr;49(6):1374-403 - PubMed
  83. Mutat Res. 2003 Jan 10;534(1-2):15-20 - PubMed
  84. Acta Oncol. 1988;27(2):83-8 - PubMed
  85. Ann N Y Acad Sci. 1961 Nov 13;95:911-9 - PubMed
  86. J Natl Cancer Inst. 1981 Nov;67(5):1079-87 - PubMed
  87. PLoS One. 2017 Feb 1;12(2):e0168581 - PubMed
  88. J Neurosci Methods. 2007 May 15;162(1-2):272-81 - PubMed
  89. Spine (Phila Pa 1976). 2012 Oct 1;37(21):E1336-42 - PubMed
  90. BMC Cancer. 2010 Jul 22;10:388 - PubMed
  91. Cell Growth Differ. 2001 Dec;12(12):623-30 - PubMed
  92. Science. 1982 Sep 10;217(4564):998-1003 - PubMed
  93. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6321-5 - PubMed
  94. Int J Cancer. 2002 Aug 1;100(4):407-13 - PubMed
  95. BMC Cancer. 2016 Feb 04;16:56 - PubMed

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