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Sun WT, Wang XC, Mak SK, et al. Activation of PERK branch of ER stress mediates homocysteine-induced BK. Oncotarget. 2017;8(31):51462-51477doi: 10.18632/oncotarget.17721.
Sun, W. T., Wang, X. C., Mak, S. K., He, G. W., Liu, X. C., Underwood, M. J., & Yang, Q. (2017). Activation of PERK branch of ER stress mediates homocysteine-induced BK. Oncotarget, 8(31), 51462-51477. https://doi.org/10.18632/oncotarget.17721
Sun, Wen-Tao, et al. "Activation of PERK branch of ER stress mediates homocysteine-induced BK." Oncotarget vol. 8,31 (2017): 51462-51477. doi: https://doi.org/10.18632/oncotarget.17721
Sun WT, Wang XC, Mak SK, He GW, Liu XC, Underwood MJ, Yang Q. Activation of PERK branch of ER stress mediates homocysteine-induced BK. Oncotarget. 2017 May 09;8(31):51462-51477. doi: 10.18632/oncotarget.17721. eCollection 2017 Aug 01. PMID: 28881660; PMCID: PMC5584261.
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Oncotarget. 2017 May 09;8(31):51462-51477. doi: 10.18632/oncotarget.17721. eCollection 2017 Aug 01.

Activation of PERK branch of ER stress mediates homocysteine-induced BK.

Oncotarget

Wen-Tao Sun, Xiang-Chong Wang, Shiu-Kwong Mak, Guo-Wei He, Xiao-Cheng Liu, Malcolm John Underwood, Qin Yang

Affiliations

  1. Division of Cardiology, Department of Medicine and Therapeutics, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Institute of Innovative Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  2. TEDA International Cardiovascular Hospital, Chinese Academy of Medical Sciences, Tianjin, China.
  3. Division of Cardiothoracic Surgery, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.

PMID: 28881660 PMCID: PMC5584261 DOI: 10.18632/oncotarget.17721

Abstract

The molecular mechanism of endoplasmic reticulum (ER) stress in vascular pathophysiology remains inadequately understood. We studied the role of ER stress in homocysteine-induced impairment of coronary dilator function, with uncovering the molecular basis of the effect of ER stress on smooth muscle large-conductance Ca

Keywords: cardiovascular risk factors; coronary circulation; endoplasmic reticulum stress; homocysteine; smooth muscle cell

Conflict of interest statement

CONFLICTS OF INTEREST None.

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