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Asian J Transfus Sci. 2017 Jul-Dec;11(2):124-130. doi: 10.4103/ajts.AJTS_57_16.

Dedicated donor unit transfusions reduces donor exposure in pediatric surgery patients.

Asian journal of transfusion science

Satyam Arora, Neelam Marwaha, Hari Krishan Dhawan, K L N Rao

Affiliations

  1. Department of Transfusion Medicine, BLK Super Speciality Hospital, New Delhi, India.
  2. Department of Transfusion Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  3. Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

PMID: 28970679 PMCID: PMC5613418 DOI: 10.4103/ajts.AJTS_57_16

Abstract

BACKGROUND: Many strategies have been explored to reduce multiple donor exposures in neonates such as use of restrictive transfusion protocols, limiting iatrogenic blood loss, use of recombinant erythropoietin and single donor programs.

METHOD: In our study we assessed the feasibility of dedicating single donor units with reserving all the components from the same donor for the specified neonates/infants undergoing surgery and estimating reduction of donor exposure. Fifty neonates undergoing surgery were included in the prospective study group and the transfusion details were compared with 50 retrospective cases with same inclusion criteria.

RESULTS: An intra-operative blood loss of >13 ml/Kg was significantly associated with transfusion (

CONCLUSION: Our study showed that by practicing dedicated donor unit transfusion policy, for neonates undergoing surgery we could significantly reduce the donor exposure.

Keywords: Dedicated donor units; donor exposure; intraoperative blood loss neonatal transfusion

Conflict of interest statement

There are no conflicts of interest.

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