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Pneumonia (Nathan). 2017 Aug 25;9:12. doi: 10.1186/s41479-017-0036-z. eCollection 2017.

Atypical bacterial pneumonia in the HIV-infected population.

Pneumonia (Nathan Qld.)

Breanne M Head, Adriana Trajtman, Zulma V Rueda, Lázaro Vélez, Yoav Keynan

Affiliations

  1. Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada.
  2. Facultad de Medicina, Universidad Pontificia Bolivariana, Medellin, Colombia.
  3. Grupo Investigador de Problemas en Enfermedades Infecciosas, Universidad de Antioquia UdeA, Medellin, Colombia.
  4. Department of Internal Medicine, University of Manitoba, Winnipeg, Canada.
  5. Department of Community Health Sciences, University of Manitoba, Winnipeg, Canada.

PMID: 28856082 PMCID: PMC5571654 DOI: 10.1186/s41479-017-0036-z

Abstract

Human immunodeficiency virus (HIV)-infected individuals are more susceptible to respiratory tract infections by other infectious agents (viruses, bacteria, parasites, and fungi) as their disease progresses to acquired immunodeficiency syndrome. Despite effective antiretroviral therapy, bacterial pneumonia (the most frequently occurring HIV-associated pulmonary illness) remains a common cause of morbidity and mortality in the HIV-infected population. Over the last few decades, studies have looked at the role of atypical bacterial pneumonia (i.e. pneumonia that causes an atypical clinical presentation or responds differently to typical therapeutics) in association with HIV infection. Due to the lack of available diagnostic strategies, the lack of consideration, and the declining immunity of the patient, HIV co-infections with atypical bacteria are currently believed to be underreported. Thus, following an extensive database search, this review aimed to highlight the current knowledge and gaps regarding atypical bacterial pneumonia in HIV. The authors discuss the prevalence of

Keywords: Atypical; Bacteria; Chlamydophila; Coxiella; HIV; Legionella; Mycoplasma; Pneumonia; Tropheryma

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