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Clin Exp Hepatol. 2016 Dec;2(4):138-143. doi: 10.5114/ceh.2016.63870. Epub 2016 Nov 28.

Efficacy of HCV treatment in Poland at the turn of the interferon era - the EpiTer study.

Clinical and experimental hepatology

Robert Flisiak, Joanna Pogorzelska, Hanna Berak, Andrzej Horban, Iwona Orłowska, Krzysztof Simon, Ewelina Tuchendler, Grzegorz Madej, Anna Piekarska, Maciej Jabłkowski, Zbigniew Deroń, Włodzimierz Mazur, Marcin Kaczmarczyk, Ewa Janczewska, Arkadiusz Pisula, Jacek Smykał, Krzysztof Nowak, Marek Matukiewicz, Waldemar Halota, Joanna Wernik, Katarzyna Sikorska, Iwona Mozer-Lisewska, Błażej Rozpłochowski, Aleksander Garlicki, Krzysztof Tomasiewicz, Joanna Krzowska-Firych, Barbara Baka-Ćwierz, Wiesław Kryczka, Dorota Zarębska-Michaluk, Iwona Olszok, Anna Boroń-Kaczmarska, Barbara Sobala-Szczygieł, Bronisława Szlauer, Bogumiła Korcz-Ondrzejek, Jerzy Sieklucki, Robert Pleśniak, Agata Ruszała, Barbara Postawa-Kłosińska, Jolanta Citko, Anna Lachowicz-Wawrzyniak, Joanna Musialik, Edyta Jezierska, Witold Dobracki, Beata Dobracka, Jan Hałubiec, Rafał Krygier, Anna Strokowska, Wojciech Chomczyk, Krystyna Witczak-Malinowska

Affiliations

  1. Department of Infectious Diseases and Hepatology, Medical University of Bialystok, Poland.
  2. Daily Unit, Hospital of Infectious Diseases in Warsaw, Poland.
  3. Division of Infectious Diseases and Hepatology, Wroc?aw Medical University, Poland.
  4. 2 Department of Infectious Diseases, Voivodship Specialist Hospital, Wroclaw, Poland.
  5. Department of Infectious Diseases and Hepatology, Medical University of Lodz, Poland.
  6. Department of Infectious Diseases and Liver Diseases, Medical University of Lodz, Poland.
  7. Unit of Infectious Diseases, WSSz Bieganski, Lodz, Poland.
  8. Clinical Department of Infectious Diseases, Medical University of Silesia, Katowice, Poland.
  9. ID Clinic, Mys?owice, Poland.
  10. NZOZ LSPChW sp. z o.o. Zielona Góra, Poland.
  11. Department of Infectious Diseases and Hepatology, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
  12. Infectious Diseases Department/Department of Tropical Medicine and Epidemiology, Medical University of Gda?sk, Poland.
  13. Department of Infectious Diseases, Poznan University of Medical Sciences, Poland.
  14. Department of Infectious and Tropical Diseases, Jagiellonian University Collegium Medicum, Kraków, Poland.
  15. Department of Infectious Diseases and Hepatology, Medical University of Lublin, Poland.
  16. The Regional Center for Diagnosis and Treatment of Viral Hepatitis and Hepatology, The John Paul II Hospital in Krakow, Poland.
  17. Department of Infectious Diseases, Voivodship Hospital and Jan Kochanowski University, Kielce, Poland.
  18. Infectious Diseases Ward, Raciborz District Hospital, Poland.
  19. Department of Infectious Disease, Medical University of Silesia, Katowice, Poland.
  20. Group of Health Care Facilities in Cieszyn, Poland.
  21. Clinical Department of Infectious Diseases, Medical Center in ?a?cut, Poland.
  22. Infectious Diseases Ward, The Stefan Zeromski Specialist Municipal Hospital in Krakow, Poland.
  23. Medical Practice of Infectious Diseases, Regional Hospital, Olsztyn, Poland.
  24. Gizycko Hospital LLC, Poland.
  25. School of Medicine in Katowice, Medical University of Silesia in Katowice, Poland, Department of Gastroenterology and Hepatology, Department of Nephrology, Transplantology and Internal Diseases.
  26. Department of Infectious Diseases, Voivodship Specialist Hospital, Czestochowa, Poland.
  27. MED-FIX Centrum Medyczne Wroc?aw, Poland.
  28. Department of Infectious Diseases in Boleslawiec, Poland.
  29. Infectious Diseases and Hepatology Outpatient Clinic NZOZ "Gemini", Zychlin, Poland.
  30. Ward of Infectious Diseases, 107 Military Hospital in Walcz, Poland.
  31. University Centre of Maritime Medicine and Tropical Disease in Gdynia, Poland.

PMID: 28856278 PMCID: PMC5497429 DOI: 10.5114/ceh.2016.63870

Abstract

THE AIM OF THE STUDY: Was to analyze the efficacy achieved with regimens available for chronic hepatitis C (CHC) in Poland between 2013 and 2016.

MATERIAL AND METHODS: Data were collected from 29 centers and included 6786 patients with available sustained virologic response (SVR) data between 1 January 2013 and 31 March 2016.

RESULTS: The sustained virologic response rate for genotypes (G) 1a, 1b, 2, 3 and 4 was 62%, 56%, 92%, 67% and 56% respectively; 71% patients (

CONCLUSIONS: We observed significant differences in efficacy of HCV regimens available in Poland at the turn of the interferon era. The data will be useful as a comparison for therapeutic options expected in the next few years.

Keywords: hepatitis C; liver; therapy

References

  1. Pol Merkur Lekarski. 2004 Apr;16(94):353-7 - PubMed
  2. Int J Cancer. 2006 Jun 15;118(12):3030-44 - PubMed
  3. Przegl Epidemiol. 2005;59(3):651-60 - PubMed
  4. Nat Clin Pract Gastroenterol Hepatol. 2008 Nov;5(11):610-22 - PubMed
  5. Eur J Gastroenterol Hepatol. 2011 Nov;23(12):1213-7 - PubMed
  6. J Hepatol. 2013 Sep;59(3):434-41 - PubMed
  7. Liver Int. 2014 Jan;34(1):6-11 - PubMed
  8. Expert Opin Emerg Drugs. 2013 Dec;18(4):461-75 - PubMed
  9. Eur J Gastroenterol Hepatol. 2015 Jan;27(1):70-6 - PubMed
  10. J Viral Hepat. 2015 Jan;22 Suppl 1:26-45 - PubMed
  11. Lancet. 2015 Jun 20;385(9986):2502-9 - PubMed
  12. Expert Opin Investig Drugs. 2015;24(9):1229-39 - PubMed
  13. Gastroenterology. 2015 Nov;149(6):1462-70 - PubMed
  14. Medicine (Baltimore). 2015 Sep;94(38):e1411 - PubMed
  15. Aliment Pharmacol Ther. 2016 Nov;44(9):946-956 - PubMed
  16. Gastroenterol Hepatol (N Y). 2016 Jun;12(6 Suppl 2):1-22 - PubMed
  17. Clin Exp Hepatol. 2016 Jun;2(2):27-33 - PubMed

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