Display options
Cite
Kasaba T, Taniguchi M, Takasaki M. Effects of vagal nerves or vagosympathetic trunks stimulation on the hemodynamics during spinal anesthesia in cats. J Anesth. 1997;11(3):208-212doi: 10.1007/BF02480039.
Kasaba, T., Taniguchi, M., & Takasaki, M. (1997). Effects of vagal nerves or vagosympathetic trunks stimulation on the hemodynamics during spinal anesthesia in cats. Journal of anesthesia, 11(3), 208-212. https://doi.org/10.1007/BF02480039
Kasaba, Toshiharu, et al. "Effects of vagal nerves or vagosympathetic trunks stimulation on the hemodynamics during spinal anesthesia in cats." Journal of anesthesia vol. 11,3 (1997): 208-212. doi: https://doi.org/10.1007/BF02480039
Kasaba T, Taniguchi M, Takasaki M. Effects of vagal nerves or vagosympathetic trunks stimulation on the hemodynamics during spinal anesthesia in cats. J Anesth. 1997 Sep;11(3):208-212. doi: 10.1007/BF02480039. PMID: 28921113.
Copy Download .nbib Format: NLM
Share it on

J Anesth. 1997 Sep;11(3):208-212. doi: 10.1007/BF02480039.

Effects of vagal nerves or vagosympathetic trunks stimulation on the hemodynamics during spinal anesthesia in cats.

Journal of anesthesia

Toshiharu Kasaba, Masahiko Taniguchi, Mayumi Takasaki

Affiliations

  1. Department of Anesthesiology, Miyazaki Medical College, 5200 Kiyotake-cho, 889-16, Miyazaki, Japan.

PMID: 28921113 DOI: 10.1007/BF02480039

Abstract

PURPOSE: To clarify the sudden onset of profound bradycardia or hypotension during spinal anesthesia, we stimulated vagal nerves (VN) or vagosympathetic trunks (VST) to examine the effects on the autonomic nervous system during spinal anesthesia with different degrees of cardiac sympathetic nerve block.

METHODS: Cats were anesthetized and mechanically ventilated. The left stellate ganglion was exposed to record cardiac sympathetic nerve activity (CSNA). Systolic and diastolic blood pressures (BP), heart rate (HR), and CSNA were measured before and after intrathecal injections of 0.2, 0.5 and 1.0 ml of 1% lidocaine. After each intrathecal injection of lidocaine, bilateral VST (n=5, group A) or VN (n=5, group B) were stimulated and measurements were repeated. ]RESULTS: After 1.0 ml intrathecal injection of 1% lidocaine, CSNA was blocked completely, and BP and HR were decreased. In group A, BP were unchanged following VST stimulation while in group B, BP decreased approximately 30% by VN stimulation from the pre-stimulation levels after 0.2, 0.5, and 1.0 ml injection of 1% lidocaine, respectively. HR decreased further, approximately 35% in group A and 50% in group B, by each stimulation from the prestimulation levels after 0.2, 0.5, and 1.0 ml injection of 1% lidocaine.

CONCLUSION: These results suggest that hypotension and bradycardia during a high level of spinal anesthesia are due to the block of CSNA, and vagal reflex may produce profound hypotension and bradycardia especially in high spinal anesthesia.

Keywords: Cardiac sympathetic nerve activity; Lidocaine; Spinal; Vagal nerve stimulation; Vagosympathetic trunk stimulation

References

  1. Circ Res. 1965 Apr;16:363-75 - PubMed
  2. Anesthesiology. 1988 Jan;68(1):5-11 - PubMed
  3. Br J Anaesth. 1993 Jun;70(6):672-80 - PubMed
  4. Anesthesiology. 1974 Jul;41(1):87-9 - PubMed
  5. Anesthesiology. 1986 Aug;65(2):139-43 - PubMed
  6. Acta Anaesthesiol Scand. 1987 Aug;31(6):467-73 - PubMed
  7. J Appl Physiol. 1969 Oct;27(4):465-70 - PubMed
  8. J Neurophysiol. 1992 Jan;67(1):180-96 - PubMed
  9. Circ Res. 1973 Feb;32(2):215-20 - PubMed
  10. Anesthesiology. 1958 Jan-Feb;19(1):45-50 - PubMed
  11. Anesthesiology. 1989 May;70(5):866-8 - PubMed
  12. Brain Res. 1993 Jul 30;618(1):23-31 - PubMed
  13. Acta Anaesthesiol Scand. 1990 May;34(4):271-5 - PubMed
  14. Am Heart J. 1970 Oct;80(4):469-74 - PubMed
  15. Brain Res. 1994 May 2;644(2):233-42 - PubMed
  16. Anaesthesia. 1990 Feb;45(2):169 - PubMed

Publication Types