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Mori M, Yoshitake S, Kitano T, et al. Measurement of whole blood factor Xa-activated clotting time during hemodialysis with low-molecular-weight heparin. J Anesth. 1998;12(3):130-132doi: 10.1007/BF02480090.
Mori, M., Yoshitake, S., Kitano, T., Oda, S., & Noguchi, T. (1998). Measurement of whole blood factor Xa-activated clotting time during hemodialysis with low-molecular-weight heparin. Journal of anesthesia, 12(3), 130-132. https://doi.org/10.1007/BF02480090
Mori, Masakazu, et al. "Measurement of whole blood factor Xa-activated clotting time during hemodialysis with low-molecular-weight heparin." Journal of anesthesia vol. 12,3 (1998): 130-132. doi: https://doi.org/10.1007/BF02480090
Mori M, Yoshitake S, Kitano T, Oda S, Noguchi T. Measurement of whole blood factor Xa-activated clotting time during hemodialysis with low-molecular-weight heparin. J Anesth. 1998 Sep;12(3):130-132. doi: 10.1007/BF02480090. PMID: 28921179.
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J Anesth. 1998 Sep;12(3):130-132. doi: 10.1007/BF02480090.

Measurement of whole blood factor Xa-activated clotting time during hemodialysis with low-molecular-weight heparin.

Journal of anesthesia

Masakazu Mori, Shigenori Yoshitake, Takaaki Kitano, Shunsuke Oda, Takayuki Noguchi

Affiliations

  1. Intensive Care Unit, Oita Medical University, 1-1 Idaigaoka, Hasama-machi, 879-55, Oita, Japan.
  2. Department of Anesthesiology, Oita Medical University, 1-1 Idaigaoka, Hasama-machi, 879-55, Oita, Japan.

PMID: 28921179 DOI: 10.1007/BF02480090

Abstract

PURPOSE: To determine whole blood factor Xa-activated clotting time (XaACT), a test for monitoring low-molecular-weight heparins (LMWHs).

METHODS: Blood was obtained from six healthy volunteers. Dalteparin, a LMWH, was mixed with the blood to concentrations of 0,05 and 1.0IU·ml

RESULTS: XaACT, ACT, and APTT in dalteparin-containing blood from volunteers were correlated with dalteparin concentration (y=312.8x+86.4;r

CONCLUSION: The measurement of XaACT can be employed to monitor LMWHs in clinical settings.

Keywords: Fragmin; Hemodylasis; Low-molecular-weight heparin

References

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