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Takita K, Goda Y, Kemmotsu O, et al. Does cyclosporine affect the duration of action of vecuronium in renal transplant recipients?. J Anesth. 1995;9(3):239-242doi: 10.1007/BF02479871.
Takita, K., Goda, Y., Kemmotsu, O., Okuyama, A., Ito, T., Sakamoto, H., Mashio, H., & Kawahigashi, H. (1995). Does cyclosporine affect the duration of action of vecuronium in renal transplant recipients?. Journal of anesthesia, 9(3), 239-242. https://doi.org/10.1007/BF02479871
Takita, Koichi, et al. "Does cyclosporine affect the duration of action of vecuronium in renal transplant recipients?." Journal of anesthesia vol. 9,3 (1995): 239-242. doi: https://doi.org/10.1007/BF02479871
Takita K, Goda Y, Kemmotsu O, Okuyama A, Ito T, Sakamoto H, Mashio H, Kawahigashi H. Does cyclosporine affect the duration of action of vecuronium in renal transplant recipients?. J Anesth. 1995 Sep;9(3):239-242. doi: 10.1007/BF02479871. PMID: 28921224.
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J Anesth. 1995 Sep;9(3):239-242. doi: 10.1007/BF02479871.

Does cyclosporine affect the duration of action of vecuronium in renal transplant recipients?.

Journal of anesthesia

Koichi Takita, Yukiko Goda, Osamu Kemmotsu, Atsushi Okuyama, Tadayoshi Ito, Hiroshi Sakamoto, Hideyuki Mashio, Hiroshi Kawahigashi

Affiliations

  1. Department of Anaesthesiology and Intensive Care, Hokkaido University School of Medicine, N-15, W-7, Kita-ku, 060, Sapporo, Japan.

PMID: 28921224 DOI: 10.1007/BF02479871

Abstract

The duration of action of vecuronium was tested in 41 surgical patients to evaluate whether cyclosporine modulates the action of vecuronium. The patients were divided into three groups: 12 patients with normal renal function (group A); 14 renal transplant recipients who had received cyclosporine before surgery (group B); and 15 patients with chronic renal failure undergoing surgery other than renal transplantation and who did not receive cyclosporine (group C). The times to 10% and 20% recovery of the first twitch (REC 10 and REC 20) after intravenous administration of vecuronium 0.12 mg·kg

Keywords: Cyclosporine; Renal transplantation; Vecuronium

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