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Arimura H, Hoka S, Bosnjak ZJ, et al. Alteration of vascular capacitance and blood flow distribution during halothane anesthesia. J Anesth. 1994;8(4):467-471doi: 10.1007/BF02514628.
Arimura, H., Hoka, S., Bosnjak, Z. J., & Kampine, J. P. (1994). Alteration of vascular capacitance and blood flow distribution during halothane anesthesia. Journal of anesthesia, 8(4), 467-471. https://doi.org/10.1007/BF02514628
Arimura, Hiroyuki, et al. "Alteration of vascular capacitance and blood flow distribution during halothane anesthesia." Journal of anesthesia vol. 8,4 (1994): 467-471. doi: https://doi.org/10.1007/BF02514628
Arimura H, Hoka S, Bosnjak ZJ, Kampine JP. Alteration of vascular capacitance and blood flow distribution during halothane anesthesia. J Anesth. 1994 Dec;8(4):467-471. doi: 10.1007/BF02514628. PMID: 28921357.
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J Anesth. 1994 Dec;8(4):467-471. doi: 10.1007/BF02514628.

Alteration of vascular capacitance and blood flow distribution during halothane anesthesia.

Journal of anesthesia

Hiroyuki Arimura, Sumio Hoka, Zeijko J Bosnjak, John P Kampine

Affiliations

  1. Department of Anesthesiology, Fukuoka City Hospital, Fukuoka, Japan.
  2. Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA.
  3. Department of Anesthesiology and Critical Care Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, 812, Fukuoka, Japan.

PMID: 28921357 DOI: 10.1007/BF02514628

Abstract

We examined the effect of halothane on systemic vascular capacitance as well as on systemic vascular resistance using cardiopulmonary bypass in dogs. Venous outflows from two different vascular beds, the splanchnic and extrasplanchnic beds, were also measured. Under constant perfusion flow and constant central venous pressure, a change in reservoir blood volume inversely represented a change in systemic blood volume and then in systemic vascular capacitance, and a change in mean arterial pressure directly reflected a change in systemic vascular resistance. Administration of 1% and 2% halothane produced the blood concentrations of 0.58±0.14 mM and 1.34±0.06 mM, respectively. Systemic vascular resistance decreased by 12±6% and 40±4% during 1% and 2% halothane, respecitively. Systemic blood volume increased by 7±2 ml·kg

Keywords: Blood flow distribution; Blood volume; Halothane; Splanchnic; Vascular capacitance; Vein

References

  1. Fed Proc. 1983 Apr;42(6):1678-84 - PubMed
  2. Am J Physiol. 1977 Feb;232(2):H152-6 - PubMed
  3. Anesthesiology. 1970 May;32(5):396-409 - PubMed
  4. Anesthesiology. 1971 Jul;35(1):81-90 - PubMed
  5. Acta Anaesthesiol Scand. 1974;18(2):114-22 - PubMed
  6. Circ Res. 1974 May;34(5):606-23 - PubMed
  7. Anesthesiology. 1966 Sep-Oct;27(5):654-61 - PubMed
  8. Am J Physiol. 1988 Feb;254(2 Pt 2):R212-21 - PubMed
  9. Am J Physiol. 1974 Nov;227(5):1166-72 - PubMed
  10. Anesthesiology. 1984 Dec;61(6):726-30 - PubMed
  11. Anesthesiology. 1991 Mar;74(3):539-51 - PubMed
  12. Circ Res. 1973 Jul;33(1):22-33 - PubMed
  13. Anesthesiology. 1966 Jan-Feb;27(1):24-32 - PubMed
  14. Anesthesiology. 1987 May;66(5):647-52 - PubMed
  15. Can J Physiol Pharmacol. 1985 Nov;63(11):1345-55 - PubMed
  16. Physiol Rev. 1983 Oct;63(4):1281-342 - PubMed

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