Display options
Cite
Wu FP, Peng JB, Fu LY, et al. Direct Palladium-Catalyzed Carbonylative Transformation of Allylic Alcohols and Related Derivatives. Org Lett. 2017;19(19):5474-5477doi: 10.1021/acs.orglett.7b02801.
Wu, F. P., Peng, J. B., Fu, L. Y., Qi, X., & Wu, X. F. (2017). Direct Palladium-Catalyzed Carbonylative Transformation of Allylic Alcohols and Related Derivatives. Organic letters, 19(19), 5474-5477. https://doi.org/10.1021/acs.orglett.7b02801
Wu, Fu-Peng, et al. "Direct Palladium-Catalyzed Carbonylative Transformation of Allylic Alcohols and Related Derivatives." Organic letters vol. 19,19 (2017): 5474-5477. doi: https://doi.org/10.1021/acs.orglett.7b02801
Wu FP, Peng JB, Fu LY, Qi X, Wu XF. Direct Palladium-Catalyzed Carbonylative Transformation of Allylic Alcohols and Related Derivatives. Org Lett. 2017 Oct 06;19(19):5474-5477. doi: 10.1021/acs.orglett.7b02801. Epub 2017 Sep 18. PMID: 28921991.
Copy Download .nbib Format: NLM
Share it on

Org Lett. 2017 Oct 06;19(19):5474-5477. doi: 10.1021/acs.orglett.7b02801. Epub 2017 Sep 18.

Direct Palladium-Catalyzed Carbonylative Transformation of Allylic Alcohols and Related Derivatives.

Organic letters

Fu-Peng Wu, Jin-Bao Peng, Lu-Yang Fu, Xinxin Qi, Xiao-Feng Wu

Affiliations

  1. Department of Chemistry, Zhejiang Sci-Tech University , Hangzhou, Zhejiang 310018, People's Republic of China.
  2. Leibniz-Institut für Katalyse e.V. an der, Institution Universität Rostock , Albert-Einstein-Straße 29a, Rostock 18059, Germany.

PMID: 28921991 DOI: 10.1021/acs.orglett.7b02801

Abstract

A direct, palladium-catalyzed, carbonylative transformation of allylic alcohols for the synthesis of β,γ-unsaturated carboxylic acids has been developed. With formic acid as the CO source, various allylic alcohols were conveniently transformed into the corresponding β,γ-unsaturated carboxylic acids with excellent linear and (E)-selectivity. The reaction was performed under mild conditions; toxic CO gas manipulation and high-pressure equipment were avoided in this procedure.

Publication Types