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El-Massry AA, Dowidar AM, Massoud TH, et al. Evaluation of the effect of corneal collagen cross-linking for keratoconus on the ocular higher-order aberrations. Clin Ophthalmol. 2017;11:1461-1469doi: 10.2147/OPTH.S142167.
El-Massry, A. A., Dowidar, A. M., Massoud, T. H., & Tadros, B. G. D. (2017). Evaluation of the effect of corneal collagen cross-linking for keratoconus on the ocular higher-order aberrations. Clinical ophthalmology (Auckland, N.Z.), 111461-1469. https://doi.org/10.2147/OPTH.S142167
El-Massry, Ahmed Abdel-Karim, et al. "Evaluation of the effect of corneal collagen cross-linking for keratoconus on the ocular higher-order aberrations." Clinical ophthalmology (Auckland, N.Z.) vol. 11 (2017): 1461-1469. doi: https://doi.org/10.2147/OPTH.S142167
El-Massry AA, Dowidar AM, Massoud TH, Tadros BGD. Evaluation of the effect of corneal collagen cross-linking for keratoconus on the ocular higher-order aberrations. Clin Ophthalmol. 2017 Aug 09;11:1461-1469. doi: 10.2147/OPTH.S142167. eCollection 2017. PMID: 28860694; PMCID: PMC5558591.
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Clin Ophthalmol. 2017 Aug 09;11:1461-1469. doi: 10.2147/OPTH.S142167. eCollection 2017.

Evaluation of the effect of corneal collagen cross-linking for keratoconus on the ocular higher-order aberrations.

Clinical ophthalmology (Auckland, N.Z.)

Ahmed Abdel-Karim El-Massry, Amgad Mostafa Dowidar, Tamer Hamdy Massoud, Baher Guirguis Daoud Tadros

Affiliations

  1. Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria Governorate, Egypt.

PMID: 28860694 PMCID: PMC5558591 DOI: 10.2147/OPTH.S142167

Abstract

BACKGROUND: Corneal collagen cross-linking (CXL) is the only treatment currently available to arrest the progression of keratoconus. The procedure consists of photopolymerization of stromal collagen fibers induced by combined action of a photosensitizing substance (riboflavin or vitamin B2) and ultraviolet-A light.

PURPOSE: To determine changes in the ocular higher-order aberrations (HOAs) after CXL and its correlation with changes in visual acuity.

DESIGN: Prospective interventional study.

SUBJECTS AND METHODS: This study was conducted on 30 eyes of 16 patients with progressive keratoconus documented between 2012 and 2014. Patients were treated with epithelium-off CXL and followed for a minimum of 6 months. The following ocular HOAs were measured and analyzed using I-Tracey Aberrometer: coma, trefoil, spherical aberration, astigmatism, and total HOAs.

RESULTS: There was statistically significant improvement in uncorrected visual acuity and best-corrected visual acuity between the preoperative and 6-month evaluations (

CONCLUSION: Total HOAs, total coma, and spherical aberrations decreased after CXL. Coma has a direct relationship with the improvement of visual function.

Keywords: collagen cross-linking; progressive keratoconus; ultraviolet irradiation; wavefront aberrations

Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

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