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Thiel B, Sharma A, Shaikh S. Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency. Cureus. 2017;9(7):e1506doi: 10.7759/cureus.1506.
Thiel, B., Sharma, A., & Shaikh, S. (2017). Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency. Cureus, 9(7), e1506. https://doi.org/10.7759/cureus.1506
Thiel, Bryan, et al. "Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency." Cureus vol. 9,7 (2017): e1506. doi: https://doi.org/10.7759/cureus.1506
Thiel B, Sharma A, Shaikh S. Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency. Cureus. 2017 Jul 23;9(7):e1506. doi: 10.7759/cureus.1506. PMID: 28948126; PMCID: PMC5608491.
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Cureus. 2017 Jul 23;9(7):e1506. doi: 10.7759/cureus.1506.

Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency.

Cureus

Bryan Thiel, Aman Sharma, Saad Shaikh

Affiliations

  1. University of Central Florida College of Medicine.
  2. Ophthalmology, Orlando Veterans Affairs Medical Center.
  3. Ophthalmology, University of Central Florida College of Medicine.

PMID: 28948126 PMCID: PMC5608491 DOI: 10.7759/cureus.1506

Abstract

We report a case of new onset retinitis pigmentosa (RP) associated with a glucose-6-phosphate dehydrogenase (G6PD) deficiency in a 63-year-old African-American male who presented with worsening night vision over a period of five years. The pathogenesis of G6PD-mediated oxidative biological damage is reviewed and a mechanism for the onset of retinal disease proposed.

Keywords: glucose-6-phosphate dehydrogenase deficiency; metabolism; oxidative; retinitis pigmentosa

Conflict of interest statement

The authors have declared that no competing interests exist.

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