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Narváez DM, Groot H, Diaz SM, et al. Oxidative stress and repetitive element methylation changes in artisanal gold miners occupationally exposed to mercury. Heliyon. 2017;3(9):e00400doi: 10.1016/j.heliyon.2017.e00400.
Narváez, D. M., Groot, H., Diaz, S. M., Palma, R. M., Muñoz, N., Cros, M. P., & Hernández-Vargas, H. (2017). Oxidative stress and repetitive element methylation changes in artisanal gold miners occupationally exposed to mercury. Heliyon, 3(9), e00400. https://doi.org/10.1016/j.heliyon.2017.e00400
Narváez, Diana M, et al. "Oxidative stress and repetitive element methylation changes in artisanal gold miners occupationally exposed to mercury." Heliyon vol. 3,9 (2017): e00400. doi: https://doi.org/10.1016/j.heliyon.2017.e00400
Narváez DM, Groot H, Diaz SM, Palma RM, Muñoz N, Cros MP, Hernández-Vargas H. Oxidative stress and repetitive element methylation changes in artisanal gold miners occupationally exposed to mercury. Heliyon. 2017 Sep 12;3(9):e00400. doi: 10.1016/j.heliyon.2017.e00400. eCollection 2017 Sep. PMID: 28948237; PMCID: PMC5602780.
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Heliyon. 2017 Sep 12;3(9):e00400. doi: 10.1016/j.heliyon.2017.e00400. eCollection 2017 Sep.

Oxidative stress and repetitive element methylation changes in artisanal gold miners occupationally exposed to mercury.

Heliyon

Diana M Narváez, Helena Groot, Sonia M Diaz, Ruth Marien Palma, Nathalia Muñoz, Marie-Pierre Cros, Hector Hernández-Vargas

Affiliations

  1. Human Genetics Laboratory. Universidad de los Andes. Bogotá, Colombia.
  2. Instituto Nacional de Salud (INS). Bogotá, Colombia.
  3. Epigenetics Group. International Agency for Research on Cancer (IARC). Lyon, France.

PMID: 28948237 PMCID: PMC5602780 DOI: 10.1016/j.heliyon.2017.e00400

Abstract

Mercury (Hg) exposure is a public health concern due to its persistence in the environment and its high toxicity. Such toxicity has been associated with the generation of oxidative stress in occupationally exposed subjects, such as artisanal gold miners. In this study, we characterize occupational exposure to Hg by measuring blood, urine and hair levels, and investigate oxidative stress and DNA methylation associated with gold mining. To do this, samples from 53 miners and 36 controls were assessed. We show higher levels of oxidative stress marker 8-OHdG in the miners. Differences in

Keywords: Biological sciences; Genetics; Health sciences; Public health; Toxicology

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