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Studennikov AE, Ustinov VA, Morozova VV, et al. New human single chain anti-idiotypic antibody against benzo[a]pyrene. Cent Eur J Immunol. 2017;42(2):123-130doi: 10.5114/ceji.2017.69353.
Studennikov, A. E., Ustinov, V. A., Morozova, V. V., Tikunova, N. V., & Glushkov, A. N. (2017). New human single chain anti-idiotypic antibody against benzo[a]pyrene. Central-European journal of immunology, 42(2), 123-130. https://doi.org/10.5114/ceji.2017.69353
Studennikov, Artem E, et al. "New human single chain anti-idiotypic antibody against benzo[a]pyrene." Central-European journal of immunology vol. 42,2 (2017): 123-130. doi: https://doi.org/10.5114/ceji.2017.69353
Studennikov AE, Ustinov VA, Morozova VV, Tikunova NV, Glushkov AN. New human single chain anti-idiotypic antibody against benzo[a]pyrene. Cent Eur J Immunol. 2017;42(2):123-130. doi: 10.5114/ceji.2017.69353. Epub 2017 Aug 08. PMID: 28860930; PMCID: PMC5573885.
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Cent Eur J Immunol. 2017;42(2):123-130. doi: 10.5114/ceji.2017.69353. Epub 2017 Aug 08.

New human single chain anti-idiotypic antibody against benzo[a]pyrene.

Central-European journal of immunology

Artem E Studennikov, Valentin A Ustinov, Vera V Morozova, Nina V Tikunova, Andrey N Glushkov

Affiliations

  1. Federal State Scientific Institute, Federal Research Centre for Coal and Coal Chemistry, Siberian Branch of the Russian Academy of Sciences, Institute of Human Ecology, Kemerovo, Russia.
  2. Federal State Scientific Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
  3. Federal State Educational Institute of Higher Professional Education, Kemerovo State University, Kemerovo, Russia.

PMID: 28860930 PMCID: PMC5573885 DOI: 10.5114/ceji.2017.69353

Abstract

The nal¨ve library from the lymphocytes of healthy humans was screened by murine single-stranded idiotypic antibodies against benzo[a]pyrene (pSh). The phage clone which contained of anti-idiotypic antibody against benzo[a]pyrene, designated as A4, was chosen for further work because of highly specific to pSh. The available protein databases were searched. The A4 amino acid sequence was unique and 76% identical to a sequence in antibody against interferon

Keywords: anti-idiotypic antibody; benzo[a]pyrene; immunology; phage display; polycyclic aromatic hydrocarbons; single-chain antibody

Conflict of interest statement

The authors declare no conflict of interest.

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