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El Shazly AN, Soliman DR, Assar EH, et al. Phosphate disturbance in critically ill children: Incidence, associated risk factors and clinical outcomes. Ann Med Surg (Lond). 2017;21:118-123doi: 10.1016/j.amsu.2017.07.079.
El Shazly, A. N., Soliman, D. R., Assar, E. H., Behiry, E. G., & Gad Ahmed, I. A. E. N. (2017). Phosphate disturbance in critically ill children: Incidence, associated risk factors and clinical outcomes. Annals of medicine and surgery (2012), 21118-123. https://doi.org/10.1016/j.amsu.2017.07.079
El Shazly, Ahmed Nabih, et al. "Phosphate disturbance in critically ill children: Incidence, associated risk factors and clinical outcomes." Annals of medicine and surgery (2012) vol. 21 (2017): 118-123. doi: https://doi.org/10.1016/j.amsu.2017.07.079
El Shazly AN, Soliman DR, Assar EH, Behiry EG, Gad Ahmed IAEN. Phosphate disturbance in critically ill children: Incidence, associated risk factors and clinical outcomes. Ann Med Surg (Lond). 2017 Aug 09;21:118-123. doi: 10.1016/j.amsu.2017.07.079. eCollection 2017 Sep. PMID: 28861270; PMCID: PMC5560116.
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Ann Med Surg (Lond). 2017 Aug 09;21:118-123. doi: 10.1016/j.amsu.2017.07.079. eCollection 2017 Sep.

Phosphate disturbance in critically ill children: Incidence, associated risk factors and clinical outcomes.

Annals of medicine and surgery (2012)

Ahmed Nabih El Shazly, Doaa Refaey Soliman, Effat Hussien Assar, Eman Gamal Behiry, Ibrahim Abd El Naby Gad Ahmed

Affiliations

  1. Department of Pediatrics, Faculty of Medicine, Benha University, Benha Qualubia, 13511, Egypt.
  2. Department of Pediatrics, Faculty of Medicine, Benha University, Toukh Qualubia, 13471, Egypt.

PMID: 28861270 PMCID: PMC5560116 DOI: 10.1016/j.amsu.2017.07.079

Abstract

BACKGROUND: Hypophosphatemia is one of the common disorders that develop in critically ill patients. It has potential complications and is often unrecognized in those patients.

OBJECTIVE: Determining the incidence of hypophosphatemia in critically ill children, its association with clinical outcomes and the possible risk factors.

METHODS: 50 patients were enrolled in the study. Levels of serum phosphate were measured on day 1 and day 7 of PICU (Pediatric intensive care unit) stay. The following variables were analyzed: age, gender, diagnosis on admission, malnutrition, phosphorus intake, clinical severity score on admission OFI (Organ Failure Index) and daily scores PELOD (Pediatric Logistic Organ Dysfunction), sepsis, use of dopamine, furosemide and steroids and assessment of nutrition by z scores.

RESULTS: The incidence of hypophosphatemia on admission was 42%. On seventh day of admission incidence of hypophosphatemia was 62%. Malnutrition was present in 24% of patients, serum phosphorus level was significantly lower in malnourished than in well-nourished children (

CONCLUSION: Hypophosphatemia was common in the first 7 days of PICU hospitalization and was associated with prolonged PICU stay, Significant association between hypophosphatemia and duration of use of mechanical ventilation, use of furosemide, dopamine, steroids and β2 agonist.

Keywords: Critical illness; Hypophosphatemia; Malnutrition; Phosphorus

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