Display options
Cite
Tao C, Hu X, Li H, et al. White Matter Injury after Intracerebral Hemorrhage: Pathophysiology and Therapeutic Strategies. Front Hum Neurosci. 2017;11:422doi: 10.3389/fnhum.2017.00422.
Tao, C., Hu, X., Li, H., & You, C. (2017). White Matter Injury after Intracerebral Hemorrhage: Pathophysiology and Therapeutic Strategies. Frontiers in human neuroscience, 11422. https://doi.org/10.3389/fnhum.2017.00422
Tao, Chuanyuan, et al. "White Matter Injury after Intracerebral Hemorrhage: Pathophysiology and Therapeutic Strategies." Frontiers in human neuroscience vol. 11 (2017): 422. doi: https://doi.org/10.3389/fnhum.2017.00422
Tao C, Hu X, Li H, You C. White Matter Injury after Intracerebral Hemorrhage: Pathophysiology and Therapeutic Strategies. Front Hum Neurosci. 2017 Aug 25;11:422. doi: 10.3389/fnhum.2017.00422. eCollection 2017. PMID: 28890692; PMCID: PMC5575148.
Copy Download .nbib Format: NLM
Share it on

Front Hum Neurosci. 2017 Aug 25;11:422. doi: 10.3389/fnhum.2017.00422. eCollection 2017.

White Matter Injury after Intracerebral Hemorrhage: Pathophysiology and Therapeutic Strategies.

Frontiers in human neuroscience

Chuanyuan Tao, Xin Hu, Hao Li, Chao You

Affiliations

  1. Stroke Clinical Research Unit, Department of Neurosurgery, West China Hospital, Sichuan UniversityChengdu, China.

PMID: 28890692 PMCID: PMC5575148 DOI: 10.3389/fnhum.2017.00422

Abstract

Intracerebral hemorrhage (ICH) accounts for 10%-30% of all types of stroke. Bleeding within the brain parenchyma causes gray matter (GM) destruction as well as proximal or distal white matter (WM) injury (WMI) due to complex pathophysiological mechanisms. Because WM has a distinct cellular architecture, blood supply pattern and corresponding function, and its response to stroke may vary from that of GM, a better understanding of the characteristics of WMI following ICH is essential and may shed new light on treatment options. Current evidence using histological, radiological and chemical biomarkers clearly confirms the spatio-temporal distribution of WMI post- ICH. Although certain types of pathological damage such as inflammatory, oxidative and neuro-excitotoxic injury to WM have been identified, the exact molecular mechanisms remain unclear. In this review article, we briefly describe the constitution and physiological function of brain WM, summarize evidence regarding WMI, and focus on the underlying pathophysiological mechanisms and therapeutic strategies.

Keywords: axonal damage; demyelination; intracerebral hemorrhage; pathophysiology; treatment; white matter injury

References

  1. J Neurosurg. 2000 Jan;92(1):58-63 - PubMed
  2. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5621-6 - PubMed
  3. Cell Mol Biol (Noisy-le-grand). 2000 May;46(3):673-83 - PubMed
  4. Brain. 2000 Sep;123 ( Pt 9):1850-62 - PubMed
  5. AJNR Am J Neuroradiol. 2001 Jan;22(1):143-51 - PubMed
  6. N Engl J Med. 2001 May 10;344(19):1450-60 - PubMed
  7. Eur Neurol. 2002;47(1):45-51 - PubMed
  8. AJNR Am J Neuroradiol. 2002 Sep;23(8):1334-41 - PubMed
  9. Dev Neurosci. 2002;24(2-3):154-60 - PubMed
  10. Bioessays. 2003 Apr;25(4):346-55 - PubMed
  11. Crit Care Med. 2003 May;31(5):1482-9 - PubMed
  12. Neuroimage. 2003 Nov;20(3):1714-22 - PubMed
  13. J Neurotrauma. 2004 Jun;21(6):754-74 - PubMed
  14. Stroke. 2005 Mar;36(3):e23-41 - PubMed
  15. J Neurotrauma. 2005 Mar;22(3):407-14 - PubMed
  16. Curr Neurovasc Res. 2005 Apr;2(2):149-55 - PubMed
  17. Acta Neurochir Suppl. 2006;96:177-82 - PubMed
  18. Stroke. 2006 Oct;37(10):2508-13 - PubMed
  19. J Neurosci Res. 2007 Jan;85(1):213-22 - PubMed
  20. J Neurosci Res. 2007 May 15;85(7):1436-48 - PubMed
  21. Exp Neurol. 2007 Jul;206(1):43-52 - PubMed
  22. J Anat. 2007 Jun;210(6):693-702 - PubMed
  23. Exp Neurol. 2008 Dec;214(2):266-75 - PubMed
  24. Ann N Y Acad Sci. 2008 Oct;1142:266-309 - PubMed
  25. Neurosci Res. 2009 Feb;63(2):100-5 - PubMed
  26. Stroke. 2009 Jun;40(6):2241-3 - PubMed
  27. Neuron Glia Biol. 2009 May;5(1-2):29-34 - PubMed
  28. Biol Pharm Bull. 2009 Oct;32(10):1639-44 - PubMed
  29. Nature. 2009 Oct 15;461(7266):983-6 - PubMed
  30. Cerebrovasc Dis. 2010;29(6):564-70 - PubMed
  31. Neurosurgery. 2010 Aug;67(2):357-65; discussion 365-6 - PubMed
  32. Dev Neurosci. 2010;32(5-6):396-405 - PubMed
  33. Stroke. 2010 Oct;41(10 Suppl):S107-10 - PubMed
  34. AJNR Am J Neuroradiol. 2011 Jan;32(1):85-91 - PubMed
  35. J Anat. 2011 Jul;219(1):53-64 - PubMed
  36. J Neuropathol Exp Neurol. 2011 Mar;70(3):218-35 - PubMed
  37. J Cereb Blood Flow Metab. 2011 Aug;31(8):1743-50 - PubMed
  38. Neurochem Res. 2011 Dec;36(12):2287-91 - PubMed
  39. Brain. 2012 Apr;135(Pt 4):1268-80 - PubMed
  40. Glia. 2012 May;60(6):875-81 - PubMed
  41. Clin Biochem. 2012 Nov;45(16-17):1320-4 - PubMed
  42. Neurocrit Care. 2012 Dec;17(3):401-7 - PubMed
  43. Acta Neuropathol. 2012 Dec;124(6):847-60 - PubMed
  44. J Neurosci Res. 2013 Feb;91(2):240-8 - PubMed
  45. CNS Neurosci Ther. 2012 Dec;18(12):1003-11 - PubMed
  46. J Clin Invest. 2013 Feb;123(2):782-6 - PubMed
  47. NMR Biomed. 2013 Jul;26(7):810-28 - PubMed
  48. J Neurosci. 2013 Jan 30;33(5):1759-72 - PubMed
  49. Br J Anaesth. 2013 Sep;111(3):424-32 - PubMed
  50. Neurol Res. 2013 Oct;35(8):829-36 - PubMed
  51. PLoS One. 2013 May 31;8(5):e65140 - PubMed
  52. Mol Cells. 2013 Jul;36(1):17-24 - PubMed
  53. Clin Chim Acta. 2013 Sep 23;424:182-6 - PubMed
  54. Nat Neurosci. 2013 Sep;16(9):1211-1218 - PubMed
  55. Neurosci Res. 2014 Jan;78:45-9 - PubMed
  56. J Am Heart Assoc. 2013 Aug 02;2(4):e000090 - PubMed
  57. Springerplus. 2013 Jul 30;2:358 - PubMed
  58. J Cereb Blood Flow Metab. 2013 Dec;33(12):1921-7 - PubMed
  59. Neurocrit Care. 2014 Aug;21(1):152-62 - PubMed
  60. Cell Mol Life Sci. 2014 Mar;71(6):1055-66 - PubMed
  61. Neuroscience. 2014 Sep 12;276:148-60 - PubMed
  62. Stroke. 2014 Jan;45(1):290-2 - PubMed
  63. NMR Biomed. 2014 Feb;27(2):163-74 - PubMed
  64. Glia. 2014 Feb;62(2):272-83 - PubMed
  65. J Res Med Sci. 2013 Dec;18(12):1061-6 - PubMed
  66. Exp Neurol. 2014 May;255:113-26 - PubMed
  67. Brain Res. 2014 Jul 29;1574:70-6 - PubMed
  68. Ann Neurol. 2014 Aug;76(2):252-68 - PubMed
  69. J Neurosci. 2014 Jun 18;34(25):8467-73 - PubMed
  70. PLoS One. 2014 Jun 24;9(6):e97946 - PubMed
  71. J Neurol Neurosurg Psychiatry. 2015 May;86(5):565-73 - PubMed
  72. Hum Brain Mapp. 2014 Dec;35(12):5877-87 - PubMed
  73. J Cereb Blood Flow Metab. 2014 Nov;34(11):1837-47 - PubMed
  74. J Neurosurg. 2014 Nov;121(5):1232-8 - PubMed
  75. Semin Ultrasound CT MR. 2014 Oct;35(5):432-44 - PubMed
  76. Neuroimage Clin. 2014 Aug 07;6:32-42 - PubMed
  77. Stroke. 2015 Feb;46(2):361-8 - PubMed
  78. Mol Neurobiol. 2016 Mar;53(2):1310-21 - PubMed
  79. Brain Behav Immun. 2015 May;46:293-310 - PubMed
  80. Brain Res. 2015 Oct 14;1623:123-34 - PubMed
  81. Mol Immunol. 2015 Jun;65(2):267-76 - PubMed
  82. Neurobiol Dis. 2015 May;77:13-25 - PubMed
  83. Exp Neurol. 2015 Oct;272:128-34 - PubMed
  84. Neuron. 2015 Mar 18;85(6):1227-43 - PubMed
  85. Stroke. 2015 May;46(5):1328-36 - PubMed
  86. Mult Scler. 2015 Aug;21(9):1095-103 - PubMed
  87. Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168B(5):317-26 - PubMed
  88. Glia. 2015 Oct;63(10):1840-9 - PubMed
  89. Brain Res. 2015 Oct 14;1623:135-49 - PubMed
  90. Neurol Res. 2015 Sep;37(9):774-81 - PubMed
  91. Exp Neurol. 2015 Oct;272:88-96 - PubMed
  92. Neuroimage. 2015 Sep;118:334-43 - PubMed
  93. Brain. 2015 Sep;138(Pt 9):2608-18 - PubMed
  94. Am J Pathol. 2015 Sep;185(9):2431-40 - PubMed
  95. PLoS One. 2015 Jul 24;10(7):e0133783 - PubMed
  96. Neuroradiology. 2016 Jan;58(1):3-10 - PubMed
  97. J Neurosci. 2015 Oct 14;35(41):14002-8 - PubMed
  98. Nat Neurosci. 2015 Dec;18(12):1737-45 - PubMed
  99. Future Med Chem. 2015;7(15):2065-86 - PubMed
  100. J Neurochem. 2016 Oct;139 Suppl 2:91-114 - PubMed
  101. J Neuroinflammation. 2015 Nov 09;12:206 - PubMed
  102. Transl Stroke Res. 2016 Jun;7(3):192-208 - PubMed
  103. Mol Cell Neurosci. 2016 Apr;72:64-71 - PubMed
  104. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1937-42 - PubMed
  105. Oxid Med Cell Longev. 2016;2016:3215391 - PubMed
  106. J Stroke Cerebrovasc Dis. 2016 May;25(5):1102-1109 - PubMed
  107. Mol Neurobiol. 2017 Apr;54(3):1874-1886 - PubMed
  108. J Int Med Res. 2016 Jun;44(3):419-32 - PubMed
  109. Prog Neurobiol. 2016 Jun;141:45-60 - PubMed
  110. Stroke. 2016 Jun;47(6):1626-31 - PubMed
  111. J Neurosurg. 2017 Apr;126(4):1131-1139 - PubMed
  112. Neuroradiology. 2016 Oct;58(10):1043-1050 - PubMed
  113. J Neurosurg. 2017 Jun;126(6):1855-1862 - PubMed
  114. Front Cell Dev Biol. 2016 Jun 28;4:71 - PubMed
  115. Oncotarget. 2016 Nov 8;7(45):73903-73911 - PubMed
  116. Brain Circ. 2016 Jan-Mar;2(1):28-47 - PubMed
  117. Stroke. 1984 Jan-Feb;15(1):138-44 - PubMed

Publication Types