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EJNMMI Res. 2017 Aug 31;7(1):72. doi: 10.1186/s13550-017-0318-8.

Gut microbiota and physiologic bowel .

EJNMMI research

Ji Yeon Kang, Han-Na Kim, Yoosoo Chang, Yeojun Yun, Seungho Ryu, Hocheol Shin, Hyung-Lae Kim

Affiliations

  1. Department of Nuclear Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  2. Department of Biochemistry, Ewha Womans University, School of Medicine, 1071, Anyangcheon-ro, Yangcheon-gu, Seoul, 07985, South Korea.
  3. Department of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  4. Department of Family Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29, Saemunan-ro, Jongnogu, Seoul, 03181, South Korea. [email protected].
  5. Department of Biochemistry, Ewha Womans University, School of Medicine, 1071, Anyangcheon-ro, Yangcheon-gu, Seoul, 07985, South Korea. [email protected].

PMID: 28861740 PMCID: PMC5578947 DOI: 10.1186/s13550-017-0318-8

Abstract

BACKGROUND: We investigated the association between physiologic bowel FDG uptake and gut microbiota. FDG uptake in the normal large and small intestine is widely variable both in distribution and intensity. The etiology of physiologic bowel

RESULTS: We included 63 healthy male subjects. After overnight fasting, blood samples and

CONCLUSION: We cautiously speculate that physiologic bowel FDG activity might be caused by an increase in intestinal permeability and may reflect an impaired barrier function in the intestine.

Keywords: 18F-FDG PET; Gut microbiota; Intestinal; Permeability; Physiologic

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