Display options
Cite
Kaneda Y, Noda H, Endo Y, et al. . World J Gastrointest Oncol. 2017;9(9):372-378doi: 10.4251/wjgo.v9.i9.372.
Kaneda, Y., Noda, H., Endo, Y., Kakizawa, N., Ichida, K., Watanabe, F., Kato, T., Miyakura, Y., Suzuki, K., & Rikiyama, T. (2017). . World journal of gastrointestinal oncology, 9(9), 372-378. https://doi.org/10.4251/wjgo.v9.i9.372
Kaneda, Yuji, et al. "." World journal of gastrointestinal oncology vol. 9,9 (2017): 372-378. doi: https://doi.org/10.4251/wjgo.v9.i9.372
Kaneda Y, Noda H, Endo Y, Kakizawa N, Ichida K, Watanabe F, Kato T, Miyakura Y, Suzuki K, Rikiyama T. . World J Gastrointest Oncol. 2017 Sep 15;9(9):372-378. doi: 10.4251/wjgo.v9.i9.372. PMID: 28979719; PMCID: PMC5605337.
Copy Download .nbib Format: NLM
Share it on

World J Gastrointest Oncol. 2017 Sep 15;9(9):372-378. doi: 10.4251/wjgo.v9.i9.372.

[No title available]

World journal of gastrointestinal oncology

Yuji Kaneda, Hiroshi Noda, Yuhei Endo, Nao Kakizawa, Kosuke Ichida, Fumiaki Watanabe, Takaharu Kato, Yasuyuki Miyakura, Koichi Suzuki, Toshiki Rikiyama

Affiliations

  1. Department of Surgery, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
  2. Department of Surgery, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan. [email protected].

PMID: 28979719 PMCID: PMC5605337 DOI: 10.4251/wjgo.v9.i9.372

Abstract

AIM: To assess the usefulness of

METHODS: We retrospectively reviewed the database of Saitama Medical Center, Jichi Medical University, between January 2009 and December 2016. During this time, 299 patients underwent radical right hemicolectomy for right-sided colon cancer. Among them, 5 underwent RHCPD for LARCC with tumor infiltration to adjacent organs. Preoperative computed tomography (CT) was routinely performed to evaluate local tumor infiltration into adjacent organs. During the operation, we evaluated the resectability and the amount of infiltration into the adjacent organs without dissecting the adherent organs from the cancer. When we confirmed that radical resection was feasible and could lead to R0 resection, we performed RHCPD. The clinical data were carefully reviewed, and the demographic variables, intraoperative data, and postoperative parameters were recorded.

RESULTS: The median age of the 5 patients who underwent RHCPD for LARCC was 70 years. The tumors were located in the ascending colon (three patients) and transverse colon (two patients). Preoperative CT revealed infiltration of the tumor into the duodenum in all patients, the pancreas in four patients, the superior mesenteric vein (SMV) in two patients, and tumor thrombosis in the SMV in one patient. We performed RHCPD plus SMV resection in three patients. Major postoperative complications occurred in 3 patients (60%) as pancreatic fistula (grade B and grade C, according to International Study Group on Pancreatic Fistula Definition) and delayed gastric empty. None of the patients died during their hospital stay. A histological examination confirmed malignant infiltration into the duodenum and/or pancreas in 4 patients (80%), and no patients showed any malignant infiltration into the SMV. Two patients were histologically confirmed to have tumor thrombosis in the SMV. All of the tumors had clear resection margins (R0). The median follow-up time was 77 mo. During this period, two patients with tumor thrombosis died from liver metastasis. The overall survival rates were 80% at 1 year and 60% at 5 years. All patients with node-negative status (

CONCLUSION: This study showed that the long-term survival is possible for patients with LARCC if RHCPD is performed successfully, particularly in those with node-negative status.

Keywords: Inflammatory adhesion; Locally advanced right-sided colon cancer; Malignant infiltration; Pancreaticoduodenectomy; Right hemicolectomy

Conflict of interest statement

Conflict-of-interest statement: The authors declare no conflicts of interest in relation to this article.

References

  1. Surg Clin North Am. 1993 Feb;73(1):117-29 - PubMed
  2. Yonsei Med J. 2009 Dec 31;50(6):803-6 - PubMed
  3. Surg Gynecol Obstet. 1953 Aug;97(2):177-82 - PubMed
  4. Clin Radiol. 2010 Sep;65(9):708-19 - PubMed
  5. Arq Gastroenterol. 2009 Apr-Jun;46(2):151-3 - PubMed
  6. Zhonghua Wei Chang Wai Ke Za Zhi. 2011 May;14(5):372-4 - PubMed
  7. Int J Colorectal Dis. 2006 Apr;21(3):265-8 - PubMed
  8. Lancet Oncol. 2012 Nov;13(11):1152-60 - PubMed
  9. Surg Gynecol Obstet. 1985 Oct;161(4):319-22 - PubMed
  10. Clin J Gastroenterol. 2011 Feb;4(1):24-7 - PubMed
  11. Clin J Gastroenterol. 2010 Oct;3(5):259-61 - PubMed
  12. Dis Colon Rectum. 2008 Oct;51(10):1548-51 - PubMed
  13. J Surg Oncol. 2002 Jun;80(2):100-4 - PubMed
  14. J Huazhong Univ Sci Technolog Med Sci. 2015 Apr;35(2):255-8 - PubMed
  15. Surg Today. 1999;29(9):906-10 - PubMed
  16. Am J Surg. 1992 Jun;163(6):553-9 - PubMed
  17. Dis Colon Rectum. 2013 Jul;56(7):874-80 - PubMed
  18. Eur J Surg Oncol. 2009 Jul;35(7):721-7 - PubMed
  19. Ann Surg Oncol. 2010 Jun;17(6):1471-4 - PubMed
  20. Hepatobiliary Pancreat Dis Int. 2015 Jun;14(3):320-4 - PubMed
  21. J Gastrointest Oncol. 2014 Apr;5(2):148-53 - PubMed
  22. Am J Surg. 1987 Jul;154(1):67-71 - PubMed
  23. Dis Colon Rectum. 2000 Apr;43(4):460-5 - PubMed
  24. J Am Coll Surg. 1994 Nov;179(5):587-92 - PubMed
  25. Surgery. 2005 Jul;138(1):8-13 - PubMed
  26. Curr Surg. 2005 Nov-Dec;62(6):613-7 - PubMed
  27. Asian J Surg. 2016 Sep 29;:null - PubMed

Publication Types